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Mechanisms of tau self-aggregation and neurotoxicity
(2011)
Pathological tau protein aggregates can be found in brain of patients with some of the neurodegenerative diseases collectively known as tauopathies, which include Alzheimer's disease (AD). Since tau post-translational ...
Measurement of autophagy flux in the nervous system in vivo
(2013)
Accurate methods to measure autophagic activity in vivo in neurons are not available, and most of the studies are based on correlative and static measurements of autophagy markers, leading to conflicting interpretations. ...
Caracterizaci?n de la respuesta microglial en un curso temporal postisquemia consecuente con embolismo arterial inducido experimentalmente en rata wistar
(Ibagu? : Universidad del Tolima, 2014.., 2014)
Efeitos do exercício físico e tratamento com antioxidante sobre alterações comportamentais e bioquímicas em modelo animal da Doença de Alzheimer: uma Revisão Sistemática.
(Universidade Federal de São Paulo, 2023-01-10)
O envelhecimento é um processo marcado por mudanças físicas, sociais e comportamentais e determinado não só por uma idade cronológica, mas também por aspectos individuais como, por exemplo, o estilo de vida adotado ao longo ...
Interoception primes emotional processing: Multimodal evidence from neurodegeneration
(Soc Neuroscience, 2021)
Recent frameworks in cognitive neuroscience and behavioral neurology underscore interoceptive priors as core modulators of
negative emotions. However, the field lacks experimental designs manipulating the priming of ...
Systemic Inflammation Changes the Site of RAGE Expression from Endothelial Cells to Neurons in Different Brain Areas
(Molecular Neurobiology, 2018)
Intraperitoneal melatonin is not neuroprotective in the G93ASOD1 transgenic mouse model of familial ALS and may exacerbate neurodegeneration
(Elsevier Ireland, 2013-08)
In amyotrophic lateral sclerosis (ALS) reactive oxygen species and apoptosis are implicated in disease pathogenesis. Melatonin with its anti-oxidant and anti-apoptotic properties is expected to ameliorate disease phenotype. ...
Human and animal models for translational research on neurodegeneration: Challenges and opportunities from South America
(Frontiers Media S.A., 2018-04)
Facing the alarming growth of dementia and neurodegenerative conditions has become a critical priority across the globe (Alzheimer´s Disease International, 2009;Lancet, 2015;Shah et al., 2016;Parra et al., 2018). ...