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Prevention of hypertension abrogates early inflammatory events in the retina of diabetic hypertensive rats
(Academic Press Ltd Elsevier Science LtdLondonInglaterra, 2007)
Altered Peripheral and Central Inflammatory Responses in a Mouse Model of Autism
(John Wiley & Sons Inc, 2014-04)
Increasing clinical and experimental evidence links immune and inflammatory alterations with the pathogenesis of autism spectrum disorders (ASD). Autistic individuals show signs of neuroinflammation, altered inflammatory ...
Modulation of microglia and presynaptic protein expression after mesenchymal stem cells treatment in a rat model of Alzheimer's disease
(Elsevier, 2019-09)
Objectives: Sporadic Alzheimer´s disease (sAD) is the most prevalent neurodegenerative pathology with no effective therapy until date. This disease prompts hippocampal degeneration, which in turn affects multiple cognitive ...
Regional brain susceptibility to neurodegeneration: What is the role of glial cells?
(Medknow Publications, 2020-05)
The main pathological feature of the neurodegenerative diseases is represented by neuronal death that represents the final step of a cascade of adverse/hostile events. Early in the neurodegenerative process, glial cells ...
How deep amphetamine impacts our brain and why to focus on Angiotensin II
(Nova Science Publishers, 2020)
Amphetamine is known for its stimulant effects over the central nervous system exerted mainly through noradrenergic and dopaminergic neurotransmissions. However, this psychostimulant induces long-term changes in multiple ...
Outside in: Unraveling the Role of Neuroinflammation in the Progression of Parkinson's Disease
(2018)
Neuroinflammation is one of the most important processes involved in the pathogenesis of Parkinson's disease (PD). The current concept of neuroinflammation comprises an inflammation process, which occurs in the central ...
A functional progesterone receptor is required for immunomodulation, reduction of reactive gliosis and survival of oligodendrocyte precursors in the injured spinal cord
(Pergamon-Elsevier Science Ltd, 2015-11)
The anti-inflammatory effects of progesterone have been increasingly recognized in several neuropathological models, including spinal cord inflammation. In the present investigation, we explored the regulation of proinflammatory ...
Neuropeptides and Microglial Activation in Inflammation, Pain, and Neurodegenerative Diseases
(Hindawi Publishing Corporation, 2017-01)
Microglial cells are responsible for immune surveillance within the CNS. They respond to noxious stimuli by releasing inflammatory mediators and mounting an effective inflammatory response. This is followed by release of ...
Enriched environment provides neuroprotection against experimental glaucoma
(Wiley Blackwell Publishing, Inc, 2019-10)
Glaucoma is one of the most frequent causes of visual impairment worldwide, and involves selective damage to retinal ganglion cells (RGCs) and their axons. We analyzed the effect of enriched environment (EE) housing on the ...