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Microbiological assay for gatifloxacin in pharmaceutical formulations
(Elsevier B.V., 2006-02-13)
A simple, sensitive and specific agar diffusion bioassay for the antibacterial gatifloxacin was developed using a strain of Bacillus subtilis ATCC 9372 as the test organism. Gatifloxacin could be measured in tablets and ...
Non-aqueous Titration of Gatifloxacin in Pharmaceutical Formulations using Perchloric Acid
(2003-10-01)
An inexpensive, simple, precise and rapid method for the determination of fluoroquinolone gatifloxacin in tablets is described. The procedure is based on the use of volumetric dosage in a non-aqueous medium in glacial ...
Performance characteristics of bioassay UV-spectrophotometry and high perfomance liquid chromatographic determination of gatifloxacin in tablets
(Sociedade Brasileira de Química, 2008-01-01)
The microbiological bioassay, UV-spectrophotometry and HPLC methods for assaying gatifloxacin in tablets were compared. Validation parameters such as linearity, precision, accuracy, limit of detection and limit of quantitation ...
Development and validation of an UV spectrophotometric method for determination of gatifloxacin in tablets
(2005-04-01)
A simple, sensitive and accurate spectrophotometric method was developed for the assay of gatifloxacin in raw material and tablets. Validation of the method yielded good results concerning range, linearity, precision and ...
Validation of a Stability indicating RP-HPLC Method for the Determination of Gatifloxacin in eye drops
(Research Trends, 2013-11)
A reversed-phase liquid chromatography (RP-LC) method was validated for the determination of gatifloxacin in eye drops. The LC method was carried out on a Phenomenex LiChrosphere 5 µm RP-18 100 Ǻ 125 x 4.6 mm maintained ...
Treatment of adults with community-acquired respiratory tract infections: results of a multicentric clinical trial with gatifloxacin
(Brazilian Society of Infectious Diseases, 2002-08-01)
Respiratory tract infections have an important clinical and economic impact and they are the most common indication for antibiotic use in outpatient practice. This prospective, multicenter non-controlled trial assessed the ...
Gatifloxacin, Moxifloxacin, and alofloxacin Resistance due to Mutations in the gyrA and parC Genes of Staphylococcus epidermidis Strains Isolated from Patients with ndophthalmitis, Corneal Ulcers and Conjunctivitis
(2009)
Aims: Staphylococcus epidermidis is considered a commensalbacterium; however, it is frequently isolated from ocular infectionsshowing a multidrug resistance. Ciprofloxacin-resistantstrains have been isolated from ocular ...