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Fluoroquinolone susceptibilities to methicillin-resistant and susceptible coagulase-negative Staphylococcus isolated from eye infection
(Conselho Brasileiro de Oftalmologia, 2007-03-01)
PURPOSE: To evaluate the fluoroquinolone susceptibilities of ocular isolate coagulase-negative staphylococci (CoNS), identified at the Microbiology Laboratory - UNIFESP. DESIGN: Experimental laboratory investigation. ...
Non-aqueous Titration of Gatifloxacin in Pharmaceutical Formulations using Perchloric Acid
(2003-10-01)
An inexpensive, simple, precise and rapid method for the determination of fluoroquinolone gatifloxacin in tablets is described. The procedure is based on the use of volumetric dosage in a non-aqueous medium in glacial ...
Rescue of susceptibility to second-line drugs in resistant clinical isolates of Mycobacterium tuberculosis
(Future Medicine Ltd, 2022-03-23)
Aim: Antibiotic resistance is one of the biggest threats to global health, and this study aimed better understand how the efflux pumps are related to this process in tuberculosis clinical isolates. Results: The combination ...
Orbifloxacin: A Review of Properties, Its Antibacterial Activities, Pharmacokinetic/Pharmacodynamic Characteristics, Therapeutic Use, and Analytical Methods
(2013-05-01)
Orbifloxacin is a third generation of fluoroquinolone that exhibits increased antibacterial activity against the Enterobacteriaceae, gram-negative and gram-positive bacteria, anaerobes, and mycobacteria. This drug was ...
Padrão de sensibilidade de 117 amostras clínicas de Staphylococcus aureus isoladas em 12 hospitais
(Associação Médica Brasileira, 1997-09-01)
OBJECTIVE. To evaluate the antimicrobial susceptibility pattern of oxacillin susceptible (OSSA) and resistant Staphylococcus aureus (ORSA) isolates to other antimicrobial agents that can be used for the treatment of ...
Copper(I)-Catalyzed Azide-Alkyne Cycloaddition Microwave-Assisted: Preparation of 7-(4-Substituted-1H1,2,3-Triazol-1-yl)-Fluoroquinolones
(Wiley, 2019-11)
Nowadays, the pharmaceutical industry faces the challenge of innovating and increasing the productivity of new medicines due to the increasing multidrug resistance among bacteria, viruses and fungi. The main objective of ...
Occurrence and sorption of fluoroquinolones in poultry litters and soils from sao Paulo State, Brazil
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
Animal production is one of the most expressive sectors of Brazilian agro-economy. Although antibiotics are routinely used in this activity, their occurrence, fate, and potential impacts to the local environment are largely ...
Susceptibility to β-lactams and quinolones of Enterobacteriaceae isolated from urinary tract infections in outpatients
(Sociedade Brasileira de Microbiologia, 2015-10)
The antibiotic susceptibility profile was evaluated in 71 Enterobacteriaceae isolates obtained from outpatient urine cultures in July 2010 from two health institutions in Santa Fe, Argentina. The highest rates of antibiotic ...
Escherichia coli used as a biomarker of antimicrobial resistance in pig farms of Southern Brazil
(2019-01-10)
The objective of this study was to verify the presence of antimicrobial resistant strains of Escherichia coli in pig farms and to use it as a biomarker to evaluate phenotypic and genotypic profiles of antimicrobial ...