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In silico modeling of FDA-approved drugs for discovery of therapies against neglected diseases: A drug repurposing approach
(Elsevier, 2019)
Drug repurposing (i.e., finding new therapeutic uses for already known drugs, including approved, abandoned, discontinued, and investigational drugs) is being extensively applied worldwide to expedite the development of ...
Free drug theory
(Springer, 2021)
The free drug theory (sometimes also termed free drug hypothesis) provides a conceptual framework increasingly used to understand pharmacokinetics/pharmacodynamics (PK/PD) relationships [1]. It underlines the central role ...
Determination of the geometrical diarylpropenamine isomers in feces by high-performance liquid chromatography
(1999-05-14)
Diarylpropenamine derivatives are a class of compounds which have been evaluated as potential drug candidates. Here a specific and reproducible HPLC method for the determination of cis- and trans-isomers of the unsubstituted ...
Determination of the geometrical diarylpropenamine isomers in feces by high-performance liquid chromatography
(1999-05-14)
Diarylpropenamine derivatives are a class of compounds which have been evaluated as potential drug candidates. Here a specific and reproducible HPLC method for the determination of cis- and trans-isomers of the unsubstituted ...
Validation of microscopic observation drug susceptibility testing for rapid, direct rifampicin and isoniazid drug susceptibility testing in patients receiving tuberculosis treatment
(Elsevier, 2014)
Drug susceptibility testing (DST) is often needed in patients clinically failing tuberculosis (TB) therapy. Most studies of phenotypic direct drug susceptibility tests, such as microscopic observation drug susceptibility ...
Off-label and unlicensed drug utilization in hospitalized children in Fortaleza, Brazil
(2008)
Objectives To investigate the use of drugs, the extent and pattern of unlicensed and off-label use, and the potential
relationship between off-label drug use and adverse drug reactions in northeastern Brazil. Methods A ...
High-performance liquid chromatography determination of praziquantel in tablets and raw materials
(2006-10-01)
A specific and sensitive high-performance liquid chromatographic method was developed for the assay of praziquantel in raw materials and tablets. It was also found that the excipients in the commercial tablet preparation ...
High-performance liquid chromatography determination of praziquantel in tablets and raw materials
(2006-10-01)
A specific and sensitive high-performance liquid chromatographic method was developed for the assay of praziquantel in raw materials and tablets. It was also found that the excipients in the commercial tablet preparation ...