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Adverse drug events in an intensive care unit of a university hospital
(SPRINGER, 2011)
Purpose Adverse drug events (ADEs) are harmful and occur with alarming frequency in critically ill patients. Complex pharmacotherapy with multiple medications increases the probability of a drug interaction (DI) and ADEs ...
Validation of an alternative analytical method for the quantification of antioxidant activity in plant extracts
(2013-04-15)
SUMMARY. A new method was developed to evaluate the total antioxidant activity in plant extracts, which was based on radical scavenging using 2,2'-azinobis-(3-ethylbenzothiazoline)-6-sulfonic acid. The proposed method was ...
Determination of the geometrical diarylpropenamine isomers in feces by high-performance liquid chromatography
(1999-05-14)
Diarylpropenamine derivatives are a class of compounds which have been evaluated as potential drug candidates. Here a specific and reproducible HPLC method for the determination of cis- and trans-isomers of the unsubstituted ...
Evaluation of a lens-free imager to facilitate tuberculosis diagnostics in MODS
(Elsevier, 2015)
Tuberculosis (TB) control efforts are hampered by a mismatch in diagnostic technology. Lack of adequate early diagnostics and Multi-drug resistant (MDR) detection is a critical problem in control efforts. Alternate and ...
Host pharmacokinetics and drug accumulation of anthelmintics within target helminth parasites of ruminants
(New Zealand Veterinary Assoc Inc, 2017-07)
Anthelmintic drugs require effective concentrations to be attained at the site of parasite location for a certain period to assure their efficacy. The processes of absorption, distribution, metabolism and excretion ...