Buscar
Mostrando ítems 471-480 de 1044
Epigenetic Dysregulation of Dopaminergic System by Maternal Cafeteria Diet During Early Postnatal Development
(Pergamon-Elsevier Science Ltd, 2019-11)
Dopamine is a neurotransmitter crucial for motor, motivational, and reward-related functions. Our aim was to determine the effect of a palatable maternal diet on the transcriptional regulation of dopaminergic-related genes ...
Synthesis, dopaminergic profile, and molecular dynamics calculations of N-aralkyl substituted 2-aminoindans
(Pergamon-Elsevier Science Ltd, 2008-03)
Brain dopaminergic system has a crucial role in the etiology of several neuropsychiatric disorders, including Parkinson's disease, depression, and schizophrenia. Several dopaminergic drugs are used to treat these pathologies, ...
Behavioral sensitization and cellular responses to psychostimulants are reduced in D2R knockout mice
(Wiley Blackwell Publishing, Inc, 2019-12)
Repeated cocaine exposure causes long-lasting neuroadaptations that involve alterations in cellular signaling and gene expression mediated by dopamine in different brain regions, such as the striatum. Previous studies have ...
Envolvimento dopaminérgico na modulação da resposta de estresse em peixes-zebra (Danio rerio)
(Universidade Federal de Santa MariaBrasilFarmacologiaUFSMPrograma de Pós-Graduação em FarmacologiaCentro de Ciências da Saúde, 2019-06-03)
The dopaminergic system is the subject of numerous researches due to its complexity and to have numerous pathways and receptors in the central nervous system. The release of catecholamines such as dopamine and norepinephrine, ...
uLSD1/neuroLSD1 ratio is a molecular sensor of dopaminergic transmission and a regulator of the immediate-early gene Nur77
(2020)
Immediate Early genes (IEGs) are fast and transiently induced after neuronal stimulation, and their function is closely related to synaptic plasticity and gene expression regulation. The IEG, NR4A1 (Nur77) is a transcription ...
Dopamine receptor dysregulation in hippocampus of aged rats underlies chronic pulsatile l-Dopa treatment induced cognitive and emotional alterations
(2014)
l-Dopa is the major symptomatic therapy for Parkinson's disease, which commonly occurs in elderly patients. However, the effects of chronic use on mood and cognition in old subjects remain elusive. In order to compare the ...
Dopamine receptor dysregulation in hippocampus of aged rats underlies chronic pulsatile l-Dopa treatment induced cognitive and emotional alterations
(2014)
l-Dopa is the major symptomatic therapy for Parkinson's disease, which commonly occurs in elderly patients. However, the effects of chronic use on mood and cognition in old subjects remain elusive. In order to compare the ...
Brain Control of Sexually Dimorphic Liver Function and Disease: The Endocrine Connection
(Springer/Plenum Publishers, 2019-01)
A multistep signaling cascade originates in brain centers that regulate hypothalamic growth hormone-releasing hormone (Ghrh) and somatostatin expression levels and release to control the pattern of GH secretion. This process ...
Genética de los desórdenes adictivos
(Sociedad Médica de Santiago, 2000)