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In vivo effects of TGF beta 1 on the the growth of gastric epithelium in suckling rats
(ELSEVIER SCIENCE BV, 2008)
As the content of Transforming Growth Factor-beta (TGF beta) wanes in the milk of lactating rat, an increase in TGF beta is observed in the gastric epithelia concomitant with differentiation of the glands upon weaning. ...
Differential uPA expression by TGF-beta 1 in gingival fibroblasts
(INT AMER ASSOC DENTAL RESEARCHI A D R/A A D R, 2006-02)
Transforming Growth Factor-beta 1 (TGF-beta 1) plays a key role in connective tissue remodeling and inflammation. Under pathological conditions, like periodontal disease, fibroblasts may display an altered response to this ...
TGF-beta autocrine pathway and MAPK signaling promote cell invasiveness and in vivo mammary adenocarcinoma tumor progression
(Spandidos Publ Ltd, 2012-08)
Breast cancer progression and metastasis have been linked to abnormal signaling by transforming growth factor-beta (TGF-beta) cytokines. In early-stage breast cancers, TGF-beta exhibits tumor suppressor activity by repressing ...
Fine-Tuning the TGF beta Signaling Pathway by SARA During Neuronal Development
(Frontiers Media, 2020)
Neural development is a complex process that involves critical events, including cytoskeleton dynamics and selective trafficking of proteins to defined cellular destinations. In this regard, Smad Anchor for Receptor ...
JNK mediates TGF-beta 1-induced epithelial mesenchymal transdifferentiation of mouse transformed keratinocytes
(ELSEVIER, 2006-10-02)
In this study we analyzed the role of the c-Jun N-terminal kinases (JNK) pathway in the TGF-beta 1 stimulation of urokinase-type plasminogen activator (uPA), initial stages of epithelial-mesenchymal transdifferentiation ...