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Mostrando ítems 1511-1520 de 3719
Study of the effect exerted by fructo-oligosaccharides from yacon (Smallanthus sonchifolius) root flour in an intestinal infection model with Salmonella Typhimurium
(Cambridge University Press, 2013-06)
Beneficial effects of prebiotics like inulin and fructo-oligosaccharides (FOS) have been proven in health and nutrition. Yacon (Smallanthus sonchifolius), an Andean crop, contains FOS (50 – 70 % of its dry weight) and, ...
Polymyxin B increases the depletion of T regulatory cell induced by purinergic agonist
(Elsevier, 2012)
Regulatory T cells (Treg) are important in the development of immune tolerance under normal physiological
conditions. However, in pathological situations such as cancer, Treg increases have been correlated
with bad ...
Aspergillus fumigatus produz vesículas extracelulares biologicamente ativas capazes de estimular a resposta imune in vitro e in vivo. Caracterização estrutural e funcional
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em GenéticaUFMG, 2019-07-31)
The release of biomolecules by cells of different organisms have been associated with
the secretion of extracellular vesicles, an evolutionarily conserved mechanism considered a
potent vehicle of intercellular communication. ...
Doxycycline Suppresses Microglial Activation by Inhibiting the p38 MAPK and NF-kB Signaling Pathways
(Springer, 2016-05)
In neurodegenerative diseases, the inflammatory response is mediated by activated glial cells, mainly microglia, which are the resident immune cells of the central nervous system. Activated microglial cells release ...
Tissue factor at the crossroad of coagulation and cell signaling
(Wiley Blackwell Publishing, Inc, 2018-07)
The tissue factor (TF) pathway plays a central role in hemostasis and thrombo-inflammatory diseases. Although structure-function relationships of the TF initiation complex are elucidated, new facets of the dynamic regulation ...
Linear ubiquitin assembly complex regulates lung epithelial–driven responses during influenza infection
(American Society for Clinical Investigation, 2019-11-12)
Influenza A virus (IAV) is among the most common causes of pneumonia-related death worldwide. Pulmonary epithelial cells are the primary target for viral infection and replication and respond by releasing inflammatory ...
Implicação da GTPase Rap2a na imunidade inata: expressão, ativação e seu papel em macrófagos ativados por receptores do tipo Toll (TLRs)
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Biologia CelularUFMG, 2018-09-27)
Pathogen recognition is one of the essential functions of the innate immune system, performed by pattern recognition receptors (PRRs) in several cells, such as macrophages and neutrophils. The most studied PRRs are Toll-like ...
Immunomodulatory Effects of Galectin-1 on an IgE-Mediated Allergic Conjunctivitis Model
(Assoc Research Vision Ophthalmology Inc, 2015-02-01)
PURPOSE. Galectin (Gal)-1, a lectin found at sites of immune privilege with critical role in the inflammation, has been poorly investigated in the ocular inflammatory diseases. Here, we evaluated the therapeutic potential ...