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Regeneration in zebrafish lateral line neuromasts: Expression of the neural progenitor cell marker Sox2 and proliferation-dependent and-independent mechanisms of hair cell renewal
(2007)
Mechanosensory hair cells are essential for audition in vertebrates, and in many species, have the capacity for regeneration when damaged. Regeneration is robust in the fish lateral line system as new hair cells can reappear ...
Functional consequences of immune cell adhesion to endothelial cells
(2004)
Research regarding the interactions between the endothelium and immune cells has undergone a significant expansion during the past decade. Major shifts of emphasis have been the norm, from the production of a detail catalog ...
Regulation of cell survival by resveratrol involves inhibition of NFκB-regulated gene expression in prostate cancer cells
(2009)
BACKGROUND. Polyphenols have been proposed as antitumoral agents. We have shown that resveratrol (RES) induced cell cycle arrest and promoted apoptosis in prostate cancer cells by inhibition of the PI3K pathway. The RES ...
The sulfation degree of membrane-associated proteoglycan from a hemopoietic cell line is determined by changes in the growth state of the cell
(Elsevier GmbH, 1995)
Multipotential hemopoietic progenitor cells (FDCP-mix) proliferate in culture medium supplemented with horse serum. When transferred to a medium without serum, cells do not proliferate and enter a quiescent state. Both ...
In Vitro-generated Tc17 cells Present a Memory Phenotype and serve as a reservoir of Tc1 cells In Vivo
(Frontiers Media SA, 2018)
Memory CD8(+) T cells are ideal candidates for cancer immunotherapy because they can mediate long-term protection against tumors. However, the therapeutic potential of different in vitro-generated CD8(+) T cell effector ...
Trypanosoma cruzi calreticulin: In vitro modulation of key immunogenic markers of both canine tumors and relevant immune competent cells
(Elsevier, 2020)
Recombinant calreticulin from Trypanosoma cruzi (rTcCalr), the parasite responsible for Chagas' disease, binds to Canine Transmissible Venereal Tumor (CTVT) cells from primary cultures and to a canine mammary carcinoma ...
A new model to study cell-to-cell transfer of αSynuclein in vivo
(Elsevier B.V., 2018)
© 2018 Elsevier Inc. Parkinson's disease (PD) compromises motor control due to the loss of dopaminergic neurons in the substantia nigra pars compacta. At the histopathological level, PD is characterized by the accumulation ...
Intravitreal administration of multipotent mesenchymal stromal cells triggers a cytoprotective microenvironment in the retina of diabetic mice
(BioMed Central, 2016)
Background: Diabetic retinopathy is a common complication of diabetes and the leading cause of irreversible vision
loss in the Western world. The reduction in color/contrast sensitivity due to the loss of neural cells in ...
Purinergic Signaling as a Regulator of Th17 Cell Plasticity
(Public Library Science, 2016)
T helper type 17 (Th17) lymphocytes, characterized by the production of interleukin-17 and other pro-inflammatory cytokines, are present in intestinal lamina propria and have been described as important players driving ...
Vitamin A Impairs the Reprogramming of Tregs into IL-17-Producing Cells during Intestinal Inflammation
(Hindawi Publishing, 2015)
Maintaining the identity of Foxp3+ regulatory T cells (Tregs) is critical for controlling immune responses in the gut, where an
imbalance between Tregs and T effector cells has been linked to inflammatory bowel disease. ...