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A flow cytometric procedure for the quantification of cell adhesion in complex mixtures of cells
(1999)
We present a simple non-radioactive cytometry-based assay that permits the simultaneous quantitation of cell adhesion of distinct subsets of cells contained in a mixture without any previous fractionation. The procedure ...
Therapeutic potential of hyporesponsive CD4(+) T cells in autoimmunity
(Frontiers Media, 2015)
The interaction between dendritic cells (DCs) and T cells is crucial on immunity or tolerance induction. In an immature or semi-mature state, DCs induce tolerance through T-cell deletion, generation of regulatory T cells, ...
Anti-TNF therapy in patients with rheumatoid arthritis decreases Th1 and Th17 cell populations and expands IFN-γ-producing NK cell and regulatory T cell subsets
(2011)
The aim of this work was to study the effect of anti-TNF treatment on CD4+ Th1, Th17 and regulatory T cells (Tregs), together with CD8+ T cells and NK cells from rheumatoid arthritis (RA) patients. For this purpose, 18 RA ...
Metformin prevents nerve growth factor-dependent proliferative and proangiogenic effects in epithelial ovarian cancer cells and endothelial cells
(SAGE Publications Inc., 2018)
© The Author(s), 2018. Background: Epithelial ovarian cancer (EOC) is characterized by exacerbated angiogenesis regulated by proangiogenic and growth factors. Nerve growth factor (NGF) is overexpressed in EOC where it ...
Regeneration in zebrafish lateral line neuromasts: Expression of the neural progenitor cell marker Sox2 and proliferation-dependent and -independent mechanisms of hair cell renewal
(2007)
Mechanosensory hair cells are essential for audition in vertebrates, and in many species, have the capacity for regeneration when damaged. Regeneration is robust in the fish lateral line system as new hair cells can reappear ...
Differential steroidogenic response of human luteal cell subpopulations
(Oxford University, 1996)
The differentia] capacity for steroid synthesis of human
luteal cell subpopulations was investigated in a well defined
cell culture system. Corpora lutea were enzymatically
dissociated, and the two cell types were ...
Dexamethasone and Monophosphoryl Lipid A-Modulated Dendritic Cells Promote Antigen-Specific Tolerogenic Properties on Naive and Memory CD4(+) T cells
(Frontiers Media, 2016)
Tolerogenic dendritic cells (DCs) are a promising tool to control T cell-mediated autoimmunity. Here, we evaluate the ability of dexamethasone-modulated and monophosphoryl lipid A (MPLA)-activated DCs [MPLA-tolerogenic DCs ...
CD73-mediated adenosine production promotes stem cell-like properties in mouse Tc17 cells
(Wiley & Sons, 2015)
The CD73 ectonucleotidase catalyses the hydrolysis of AMP to adenosine,
an immunosuppressive molecule. Recent evidence has demonstrated that
this ectonucleotidase is up-regulated in T helper type 17 cells when generated
in ...
Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex
(2004)
Stem cells are crucial for normal development and homeostasis, and their misbehavior may be related to the origin of cancer. Progress in these areas has been difficult because the mechanisms regulating stem cell lineages ...
Bovine derived in vitro cultures generate heterogeneous populations of antigen presenting cells
(Frontiers Media, 2019)
Antigen presenting cells (APC) of the mononuclear phagocytic system include dendritic cells (DCs) and macrophages (Macs) which are essential mediators of innate and adaptive immune responses. Many of the biological functions ...