Now showing items 21-30 of 1824
Snake venomics of Bothriechis nigroviridis reveals extreme variability among palm pitviper venoms: different evolutionary solutions for the same trophic purpose
We report the proteomic characterization and biological activities of the venom of the black-speckled palm pitviper, Bothriechis nigroviridis, a neotropical arboreal pitviper from Costa Rica. In marked contrast to other ...
Pharmacological modulation of hyperalgesia induced by Bothrops asper (terciopelo) snake venom
The ability of Bothrops asper snake venom to cause hyperalgesia was investigated in rats, using the paw pressure test. Intraplantar injection of the venom (5–15 μg/paw) caused a dose and time-related hyperalgesia, which ...
Evolution, structural features, and biochemical diversity of snake venom serine proteinases
Snake venom serine proteinases share high sequence homology and are structurally similar to mammalian serine proteinases. Detailed structural comparisons based on highresolution crystal structures highlight structural ...
Effect of various Viperidae and Crotalidae snake venoms on endothelial cells in vitro
The effect of various crotalid and viperid venoms at 10, 50 and 100 μg/ml was examined on bovine and murine endothelial cells in vitro. The venoms caused the cells to lose their processes, leading to the appearance of ...
Immunological studies on BaH1 and BaPI, two hemorrhagic metalloproteinases from the venom of the snake Bothrops asper
No immunological cross-reactivity was observed between BaH1 and BaP1, two hemorrhagic metalloproteinases isolated from B. asper venom, by gel immunodiffusion, Western blotting and neutralization studies. Cross-reactivity ...