Now showing items 21-30 of 215
Molecular Factors Influencing the Affinity of Flavonoid Compounds on PGlycoprotein Efflux Transporter
(Bentham Science Publishers, 2014-10)
The most common mechanism of the so-called multidrug resistance (MDR), is mainly associated with an over expression of P-glycoprotein (Pgp). It is an ATP-dependent transport protein that limits the intracellular accumulation ...
Digital Filters for Molecular Interaction Field Descriptors
A Priori Descriptors in QSAR: a Case of Gram-Negative Bacterial Multidrug Resistance to beta-Lactams
(Croatian Chemical SocZagrebCroácia, 2008)
Is your QSAR/QSPR descriptor real or trash?
In vitro activity of natural phenolic compounds against fluconazole-resistant Candida species: a quantitative structure–activity relationship analysis
Aims: To evaluate the antifungal activity and to analyse the structure–activity relationship of eleven natural phenolic compounds against four Candida species which are resistant to fluconazole. Methods and Results: Four ...
QSAR of progestogens: Use of a priori and computed molecular descriptors and molecular graphics
(Wiley-v C H Verlag GmbhWeinheimAlemanha, 2003)