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CK2α/CK1α chimeras are sensitive to regulation by the CK2β subunit
(2008)
The effect of CK2β on the activity of CK2α and other protein kinases that can bind this regulatory subunit is not fully understood. In an attempt to improve our understanding of this effect, chimeras of CK2α and CK1α have ...
Role of the carboxyl terminus on the catalytic activity of protein kinase CK2α subunit
(2002)
Protein kinase CK2 (also known as casein kinase 2) has catalytic (α, α′) and regulatory (β) subunits. The role of carboxyl amino acids in positions from 324 to 328 was studied for Xenopus laevis CK2α. Deletions and mutations ...
Allosteric Regulation of Protein Kinases Downstream of PI3-Kinase Signalling
(Springer, 2019)
Allostery is a basic principle that enables proteins to process and transmit cellular information. Protein kinases evolved allosteric mechanisms to transduce cellular signals to downstream signalling components or effector ...
Role of JNK isoforms in the kainic acid experimental model of epilepsy and neurodegeneration
(Frontiers in Bioscience, 2017)