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Now showing items 21-28 of 28

Insulin and glucose sensitivity, insulin secretion and beta-cell distribution in endocrine pancreas of the fruit bat Artibeus lituratus

Protzek, AOP; Rafacho, A; Viscelli, BA; Bosqueiro, JR; Cappelli, AP; Paula, FMM; Boschero, AC; Pinheiro, EC (Elsevier Science IncNew YorkEUA, 2010)

Digestive adaptations to aerial lifestyles

Price, Edwin; Brun, Antonio; Caviedes Vidal, Enrique Juan Raul; Karasow, William H. (American Physiological Society, 2015-01)

Flying vertebrates (birds and bats) are under selective pressure to reduce the size of the gut and the mass of the digesta it carries. Compared to similar sized non-flying mammals, birds and bats have smaller intestines ...

Role of redox systems on Fe3+ uptake by transformed human intestinal epithelial (Caco-2) cells

Nunez, Sarah; Alvarez Alvarez, Miguel Adrián; Smith, Pamela; Tapia Tapia, Alejandra; Glass, Larry (1994)

Caco-2 cells were used as a model of human intestinal epithelium to investigate the role of redox systems in transepithelial transport of 59Fe3+. The cells reduced Fe3+ present in the apical medium; the reduction was 50% ...

Inhibition of water absorption in human proximal tubular epithelial cells in response to Shiga toxin-2

Silberstein, Claudia Marcela; Pistone Creydt, Virginia; Gerhardt, Elizabeth; Nuñez, Pablo Alfredo; Ibarra, Cristina Adriana (Springer, 2008)

Postdiarrhea hemolytic uremic syndrome (HUS) is the most common cause of acute renal failure in children in Argentina. It is well established that Shiga toxin type 2 (Stx2) causes direct damage to glomerular endothelial ...

Acetaminophen Inhibits Intestinal P-Glycoprotein Transport Activity

Novak, Analia; Delli Carpini, Griselda; Ruiz, Maria Laura; Luquita, Marcelo Gabriel; Rubio, Modesto Carlos; Mottino, Aldo Domingo; Ghanem, Carolina Inés (Wiley, 2013-10)

Repeated acetaminophen (AP) administration modulates intestinal P-glycoprotein (P-gp) expression. Whether AP can modulate P-gp activity in a short-term fashion is unknown. We investigated the acute effect of AP on rat ...

Standardization of Caco-2 cell culture as in vitro model for intestinal permeability

Rodríguez, Yanina I.; Abalos, Ivana S.; Lozano, Verónica; Cereseto, Marina; Silberman, Nicolás G.; Chiale, Carlos; Gruñeiro, Elena; Pesce, Guido (2011)

Metabolic Adaptations In Frugivorous Bats

Protzek A.O.P.; Pinheiro E.C. (Nova Science Publishers, Inc., 2011)

Impact of the aggregation state of amphotericin B on its biopharmaceutical properties. Design of micro- and nanocarriers for oral delivery

Marcelino, Henrique Rodrigues (BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE, 2016-04-08)

This thesis is part of the development and evaluation of nanomedicines potentially able to overcome unfavorable biopharmaceutical properties of amphotericin B (AmB), a highly effective molecule used for the treatment of ...