Now showing items 31-40 of 1724
Global and Ocular Hypothermic Preconditioning Protect the Rat Retina from Ischemic Damage
(Public Library Science, 2013-04)
Retinal ischemia could provoke blindness. At present, there is no effective treatment against retinal ischemic damage. Strong evidence supports that glutamate is implicated in retinal ischemic damage. We investigated ...
TGF-β1 prevents simulated ischemia/reperfusion-induced cardiac fibroblast apoptosis by activation of both canonical and non-canonical signaling pathways
Ischemia/reperfusion injury is a major cause of myocardial death. In the heart, cardiac fibroblasts play a critical role in healing post myocardial infarction. TGF-β1 has shown cardioprotective effects in cardiac damage; ...
Heparin modulates the expression of genes encoding pro and anti-apoptotic proteins in endothelial cells exposed to intestinal ischemia and reperfusion in rats
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2014-07-01)
PURPOSE: To investigate if expression of genes encoding pro and anti-apoptotic proteins in the rat enteric endothelial cells stimulated by intestinal ischemia followed by reperfusion (IR) can be modified by treatment with ...
Beneficial effects of n-acetyl cysteine on pancreas and kidney following experimental pancreatic ischemia-reperfusion in rats
(Faculdade de Medicina / USP, 2010)
OBJECTIVE: To evaluate the protective effects of N-acetyl cysteine on the pancreas and kidney after pancreatic ischemia reperfusion injury in a rat model. METHODS AND MATERIALS: Pancreatic ischemia reperfusion was performed ...
Effect of NF kappa B Inhibition by CAPE on Skeletal Muscle Ischemia-Reperfusion Injury
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2009)
Background/Aims. Nuclear factor kappa B (NF kappa B) plays important role in the pathogenesis of skeletal muscle ischemia/reperfusion (I/R) injury. Caffeic acid phenyl ester (CAPE), a potent NF kappa B inhibitor, exhibits ...
Potentiation of ischemia-reperfusion liver injury by hyperthyroidism in the rat
Parameters related to hepatic oxidative stress, cell injury, and liver histology were determined in control rats and in animals treated with 3,3',5- triiodothyronine (T3), after in vitro perfusion under normoxic or ischemia- ...
Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2005-12)
Ischemic injuries are associated with several pathological conditions, including stroke and myocardial infarction. Several studies have indicated extensive apoptotic cell death in the infarcted area as well as in the ...
Cellular mechanisms against ischemia reperfusion injury induced by the use of anesthetic pharmacological agents
Ischemia–reperfusion (IR) cycle in the myocardium is associated with activation of an injurious cascade, thus leading to new myocardial challenges, which account for up to 50% of infarct size. Some evidence implicates ...
Acute renal ischemia model in dogs: Effects of metoprolol
(Marcel Dekker Inc, 2014)