Now showing items 21-30 of 1724
Calpain translocation and activation as pharmacological targets during myocardial ischemia/reperfusion
Calpains contribute to reperfusion-induced myocardial cell death. However, it remains controversial whether its activation occurs during ischemia or reperfusion. We investigated the regulation and time-course of calpain ...
Parecoxib reduces renal injury in an ischemia/reperfusion model in rats
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2015)
CaMKII-dependent responses to ischemia and reperfusion challenges in the heart
Ischemic heart disease is a leading cause of death, and there is considerable imperative to identify effective therapeutic interventions. Cardiomyocyte Ca2+ overload is a major cause of ischemia and reperfusion injury, ...
Insulin/NFkB protects against ischemia-induced necrotic cardiomyocyte death
In the heart, insulin controls key functions such as metabolism, muscle contraction and cell death. However, all studies have been focused on insulin action during reperfusion. Here we explore the cardioprotective action ...
Comparative study between trimetazidine and ice slush hypothermia in protection against renal ischemia/reperfusion injury in a porcine model
(Brazilian Soc Urol, 2011-09-01)
Purpose: The aim of the study was to compare the effects of renal ice slush hypothermia and the use of trimetazidine in the protection against ischemia/reperfusion (I/R) injury.Materials and Methods: Fifteen farm pigs were ...
Does propofol and isoflurane protect the kidney against ischemia/reperfusion injury during transient hyperglycemia?
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2013-03-01)
PURPOSE: To study the effect of isoflurane (Iso) or propofol (Prop) anesthesia on renal ischemia/reperfusion injury (IRI) during transient hyperglycemia. METHODS: Thirty six rats were randomly assigned into six groups of ...
Hystopathological study of the intestinal epithelium submitted to different times of programmed ischemia and twenty four hours reperfusion
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2013)