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Novel therapeutic strategies for traumatic brain injury: Acute antioxidant reinforcement
(2014)
Traumatic brain injury (TBI) is the most important cause of disability in individuals under the age of 45 years and thus represents a significant social and economic burden. Evidence strongly suggests that oxidative stress ...
Free radical scavengers, anti-inflammatory and analgesic activity of Acaena magellanica
(ROYAL PHARMACEUTICAL SOC GREAT BRITAIN, 2002-06)
Extracts of the whole plant Acaena magellanica (Rosaceae) were assessed for anti-inflammatory and analgesic activity in animal models. At 600 mg kg(-1), the global ethanolic extract (GEE), dichloromethane (DCM) and defatted ...
Revisión de epicondilitis:clínica, estudio y propuesta de protocolo de tratamiento
(Hospital Clínico Universidad de Chile, 2010)
Epicondylitis is characterized by pain localized in the insertion of the elbow`s epicondilar muscles, resulting from traumatic inflammation caused by repetitive pronationsupination`s movements. It is known that early ...
Xanthine-oxidase inhibitors and statins in chronic heart failure: Effects on vascular and functional parameters
(ELSEVIER SCIENCE INC, 2011-04)
Increased oxidative stress in heart failure (HF) leads to inflammation and endothelial dysfunction (ED). Both statins and allopurinol have known anti-oxidant properties, but their utility in HF has not been fully assessed.
Diagnosis of elephantiasis nostras verrucosa as a clinical manifestation of Kaposi's sarcoma
(2020)
Elephantiasis nostras verrucosa, a rare manifestation of Kaposi’s sarcoma, is a progressive cutaneous hypertrophy caused by chronic nonfilarial lymphedema secondary to obstruction of the lymphatic system
that can lead to ...
Gene and cell therapy on the acquisition and relapse-like binge drinking in a model of alcoholism: translational options
(Nature Publishing Group, 2019)
Studies reviewed show that lentiviral gene therapy directed either at inhibiting the synthesis of brain acetaldehyde generated from ethanol or at degrading brain acetaldehyde fully prevent ethanol intake by rats bred for ...
Induction of the myofibroblastic phenotype in human gingival fibroblasts by transforming growth factor-b1: role of RhoA-ROCK and c-Jun N-terminal kinase signaling pathways
(Blackwell Munksgaard Ltd, 2006-06-05)
Myofibroblastic differentiation is an important event
in gingival wound healing and chronic inflammation. Transforming frowth factorb
1 (TGF-b1) is a potent growth factor that has been implicated in this process.
Gingival ...
Effectiveness of infliximab in patients with Behçet syndrome and severe uveoretinitis. Report of five cases Eficacia del infliximab en pacientes con síndrome de Behçet portadores de úveo-retinitis grave
(2006)
The efficacy and safety of repeated administration of infliximab was evaluated in five patients (two men, three women) with Behçet syndrome accompanied by severe uveoretinitis. Ocular and extra ocular inflammation was ...
Systematic review: are probiotics useful in controlling gastric colonization by Helicobacter pylori?
(BLACKWELL, 2006-04-15)
Helicobacter pylori is a highly prevalent pathogen considered as an aetiological factor for gastroduodenal ulcers, and a risk factor for gastric adenocarcinoma and lymphoma in humans. Most subjects colonized by this ...
New insights on the role of lipid metabolism in the metabolic reprogramming of macrophages
(Frontiers Media, 2020)
Macrophage activation is intimately linked to metabolic reprogramming. Inflammatory (M1) macrophages are able to sustain inflammatory responses and to kill pathogens, mostly by relying on aerobic glycolysis and fatty acid ...