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Prion protein NMR structures of chickens, turtles, and frogs
(NATL ACAD SCIENCES, 2005-01-18)
The NMR structures of the recombinant prion proteins from chicken (Gallus gallus; chPrP), the red-eared slider turtle (Trachemys scripta; tPrP), and the African clawed frog (Xenopus laevis; xlPrP) are presented. The amino ...
Evidence of essential arginyl residues in rabbit muscle pyruvate kinase
(1979)
Rabbit muscle pyruvate kinase is inactivated by 2,3-butanedione in borate buffer. The inactivation follows pseudo-first-order kinetics with a calculated second-order rate constant of 4.6 m-1 min-1. The modification can be ...
Uncoupling substrate and activation functions of rotavirus NSP5: Phosphorylation of Ser-67 by casein kinase 1 is essential for hyperphosphorylation
(NATL ACAD SCIENCES, 2004-11-16)
Rotavirus NSP5 is a nonstructural protein that localizes in viro-plasms of virus-infected cells. NSP5 interacts with NSP2 and undergoes a complex post-translational hyperphosphorylation, generating species with reduced ...
A regulatory RNA is involved in RNA duplex formation and biofilm regulation in sulfolobus acidocaldarius
(Oxford University Press, 2018-05-18)
Non-coding RNAs (ncRNA) are involved in essential biological processes in all three domains of life. The regulatory potential of ncRNAs in Archaea is, however, not fully explored. In this study, RNA-seq analyses identified ...
Biochemical characterization and inhibitory effects of dinophysistoxinokadaic-1 acid and microcystine l-r on protein phosphatase 2a purified from the mussel Mytilus chilensis
(2000)
Protein phosphatases are involved in many cellular processes. One of the most abundant and best studied members of this class is protein
phosphatase type-2A (PP2A). In this study, PP2A was purified from the mussel Mytilus ...
Cloning, expression pattern and essentiality of the high-affinity copper transporter 1 (ctr1) gene in zebrafish
(ELSEVIER SCIENCE BV, 2003-11-24)
The high-affinity copper transporter 1 (Ctr1) is a highly conserved transmembrane protein that mediates the internalization of copper
ions from the extracellular medium. In this study, we have isolated the zebrafish ctr1 ...
The endoplasmic reticulum and protein trafficking in dendrites and axons
(Elsevier, 2011-04)
Neurons are highly polarized cells whose dendrites and axons extend long distances from the cell body to form synapses that mediate neuronal communication. The trafficking of membrane lipids and proteins throughout the ...
Nutritional supplement of high protein content for 2-5 year old children. Development of the formulation and acceptability Suplemento alimenticio de alto contenido proteico para niños de 2 - 5 años. Desarrollo de la formulación y aceptabilidad
(2007)
Cereal-legume combinations offer proteins of high quality due to the compensation of the existing essential amino acids. Quinua (Chenopodium quinua Willd) and lupin (Lupinus albus L.) were selected with the aim of designing ...
Senescence, Apoptosis or Autophagy?
(S. Karger AG, 2008)
Many features of aging result from the incapacity of cells to
adapt to stress conditions. When damage accumulates irreversibly,
mitotic cells from renewable tissues rely on either
of two mechanisms to avoid replication. ...
The Drosophila EKC/KEOPS complex Roles in protein synthesis homeostasis and animal growth
(Landes Bioscience, 2013)
The TOR signaling pathway is crucial
in the translation of nutritional
inputs into the protein synthesis machinery regulation, allowing animal
growth. We recently identified the Bud32 (yeast)/PRPK (human) ortholog in ...