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The nitric oxide-sensitive p21Ras-ERK pathway mediates S-nitrosoglutathione-induced apoptosis
(Elsevier B.V., 2008-05-16)
p21Ras protein plays a critical role in cellular signaling that induces either cell cycle progression or apoptosis. Nitric oxide (NO) has been consistently reported to activate p21Ras through the redox sensitive cysteine ...
A novel retrieval-dependent memory process revealed by the arrest of ERK1/2 activation in the basolateral amygdala
(Society for Neuroscience, 2018-03)
Fully consolidated fear memories can be maintained or inhibited by retrieval-dependent mechanisms depending on the degree of re-exposure to fear cues. Short exposures promote memory maintenance through reconsolidation, and ...
Estradiol-mediated axogenesis of hypothalamic neurons requires ERK1/2 and ryanodine receptors-dependent intracellular Ca2+ rise in male rats
(Frontiers Media S.A., 2019-01)
17β-estradiol (E2) induces axonal growth through extracellular signal-regulated kinase 1 and 2 (ERK1/2)-MAPK cascade in hypothalamic neurons of male rat embryos in vitro, but the mechanism that initiates these events is ...
Calcium release by ryanodine receptors mediates hydrogen peroxide-induced activation of ERK and CREB phosphorylation in N2a cells and hippocampal neurons
(2007)
Hydrogen peroxide, which stimulates ERK phosphorylation and synaptic plasticity in hippocampal neurons, has also been shown to stimulate calcium release in muscle cells by promoting ryanodine receptor redox modification ...
Raf/MEK/ERK pathway activation is required for Junín virus replication
(Society for General Microbiology, 2014)
Angiotensin II Signaling in Human Preadipose Cells: Participation of ERK1,2-Dependent Modulation of Akt
(2013-10)
The renin-angiotensin system expressed in adipose tissue has been implicated in the modulation of adipocyte formation,
glucose metabolism, triglyceride accumulation, lipolysis, and the onset of the adverse metabolic ...