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Analysis Of The Applicability And Use Of Lipinski's Rule For Central Nervous System Drugs
(Bentham Science Publ LtdSharjah, 2016)
Liposomes containing cyclodextrins or meglumine to solubilize and improve the bioavailability of poorly soluble drugs
(Elsevier Science, 2017-03-19)
Poorly soluble drug-loaded liposomes are well known for their ability to solubilize and improve the bioavailability of the carried molecules, and may provide benefits as oral drug delivery systems. In this work, we aim to ...
Bioavailability of in-feed tetracyclines is influenced to a greater extent by crude protein rather than calcium
(2014-12)
Feed is a common vehicle for tetracycline administration in animal farming. However, veterinarians and farmers often overlook that common feed components, such as proteins and calcium, may interact with these drugs and ...
Bioavailability of in-feed tetracyclines is influenced to a greater extent by crude protein rather than calcium
(2014-12)
Feed is a common vehicle for tetracycline administration in animal farming. However, veterinarians and farmers often overlook that common feed components, such as proteins and calcium, may interact with these drugs and ...
Intranasal delivery of zidovudine by PLA and PLA-PEG blend nanoparticles
(Elsevier B.V., 2010-08-16)
This study describes the preparation and evaluation of biodegradable poly(L-lactide) (PLA) and poly(L, lactide)-poly(ethylene glycol) (PLA-PEG) blend nanoparticles containing zidovudine as model drug. The prepared nanoparticles ...
Intranasal delivery of zidovudine by PLA and PLA-PEG blend nanoparticles
(Elsevier B.V., 2010-08-16)
This study describes the preparation and evaluation of biodegradable poly(L-lactide) (PLA) and poly(L, lactide)-poly(ethylene glycol) (PLA-PEG) blend nanoparticles containing zidovudine as model drug. The prepared nanoparticles ...
Pharmacokinetics, safety, and tolerability of oxfendazole in healthy volunteers: A randomized, placebo-controlled first-inhuman single-dose escalation study
(American Society for Microbiology, 2019)
Cysticercosis is a parasitic disease that frequently involves the human central nervous system (CNS), and current treatment options are limited. Oxfendazole, a veterinary medicine belonging to the benzimidazole family of ...
Absolute bioavailability determination of a sustained release theophylline DETERMINACION DE LA BIODISPONIBILIDAD ABSOLUTA DE UN COMPRIMIDO DE LIBERACION CONTROLADA DE TEOFILINA
(1993)
The absolute biovailability of a sustained release tablet developed in our laboratory was evaluated. The formulation employs acrylic resins Eudragit as the sustaining release system and tablets were obtained using conventional ...
Usefulness of salivary drug monitoring for detectign efflux transporter overexpression
(Bentham Science Publishers, 2013-09)
Background: Bioavailability (F) and clearance (CL) are two pharmacokinetic parameters difficult to differentiate from simple plasma measurement when a drug is administered orally. Venous (V) / artery (A) concentration ratio ...