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Biorelevant dissolution media
(Springer, 2021)
Biorelevant dissolution media are aqueous solutions or suspensions whose composition and physicochemical characteristics closely resemble human fluids found along the different portions of the gastrointestinal tract, ...
On the mechanisms of dissolution of montroydite [HgO(s)]: Dependence of the dissolution rate on pH, temperature, and stirring rate
(Academic Press Inc Elsevier Science, 2006-05)
The dissolution behavior of montroydite (HgO) has been studied using a fully automated system. Dissolution data under equilibrium conditions are in agreement with previously published data and indicate that HgO solubility ...
Development and validation of a dissolution test for diltiazem hydrochloride in immediate release capsules
(Sociedade Brasileira de Química, 2011-01-01)
This work describes the development and validation of a dissolution test for 60 mg of diltiazem hydrochloride in immediate release capsules. The best dissolution in vitro profile was achieved using potassium phosphate ...
Development and validation of a dissolution test for diltiazem hydrochloride in immediate release capsules
(Sociedade Brasileira de Química, 2011-01-01)
This work describes the development and validation of a dissolution test for 60 mg of diltiazem hydrochloride in immediate release capsules. The best dissolution in vitro profile was achieved using potassium phosphate ...
Força de compressão e umidade no perfil de dissolução da hidroclorotiazida
(2006-01-01)
The aim of this work was to evaluate the influence of compression force and humidity in the dissolution profile of tablets formulation. As hidroclorotyiazide presents real problems of bioavailability, it was incorporate ...
Força de compressão e umidade no perfil de dissolução da hidroclorotiazida
(2006-01-01)
The aim of this work was to evaluate the influence of compression force and humidity in the dissolution profile of tablets formulation. As hidroclorotyiazide presents real problems of bioavailability, it was incorporate ...
Pharmaceutical equivalence of Hydrochlorothiazide tablets in Argentina
(Dissolution Technologies, Inc, 2018-03)
Hydrochlorothiazide (HCTZ) is a diuretic used to treat hypertension, which belongs to Class III of the Biopharmaceutics Classification System. The present study aimed to evaluate critical quality parameters of HCTZ solid ...
Intrinsic dissolution simulation of highly and poorly soluble drugs for BCS solubility classification
(Dissolution Technologies, Inc, 2017)
Intrinsic dissolution testing allows characterizing drug substances through its dissolution rate when exposed to a specified surface area in a specific dissolution media, This can be used to determine if a drug substance ...
A discriminating dissolution method for glimepiride polymorphs
(Wiley-Blackwell, 2012-02-01)
Glimepiride, an oral antidiabetic drug, is practically insoluble in water and exists in two polymorphic forms, I and II, of which form II has higher solubility in water. Because the dissolution rate of drugs can depend on ...