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Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol
(2012)
Increasing evidence indicates that endoplasmic reticulum (ER) stress is involved in various diseases. In the human heart, ischemia/reperfusion has been correlated to ER stress, and several markers of the unfolded protein ...
Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: Arginase I is expressed in infiltrating CD68+ macrophages
(University of Chicago Press, 2008-06)
In Chagas disease, which is caused by Trypanosoma cruzi, macrophages and cardiomyocytes are the main targets of infection. Classical activation of macrophages during infection is protective, whereas alternative activation ...
Vias de sinalização alteradas no coração de camundongos com redução na expressão da proteína induzida por estresse (STI1) tratados com isoproterenol
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE FISIOLOGIA E BIOFÍSICAPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia e FarmacologiaUFMG, 2021-12-09)
Chaperone molecules have been described to play an important role during the
development of heart disease. Stress-inducible protein 1 (STI1) is an important cochaperone of the Hsp70 / Hsp90 machinery, widely studied in ...
Caracterização de culturas 3D de cardiomiócitos em substratos formados por nanofibras de acetato de celulose associadas ou não ao urucum
(Universidade Federal de Minas GeraisBrasilPrograma de Pós-Graduação em Biologia CelularUFMG, 2020-02-27)
Myocardial infarction is one of the leading causes of death worldwide. The clinical result, in some cases, is the replacement of native tissue with scar tissue leading to loss of function at that location. Tissue engineering ...
Método de elementos finitos aplicado à microscopia de desfocalização
(Universidade Federal de Minas GeraisBrasilICX - DEPARTAMENTO DE FÍSICAPrograma de Pós-Graduação em FísicaUFMG, 2022-07-22)
Defocusing microscopy is a technique that has been used at the Physics Laboratory
of Biological Systems at UFMG to characterize transparent objects, such as cells and
waveguides. Through it we can obtain morphological ...