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The role of glucose metabolism and insulin resistance in cardiac remodelling induced by cigarette smoke exposure
(2021-01-01)
The aim of this study is to evaluate whether the alterations in glucose metabolism and insulin resistance are mechanisms presented in cardiac remodelling induced by the toxicity of cigarette smoke. Male Wistar rats were ...
Cardiac remodeling induced by smoking: concepts, relevance, and potential mechanisms
(Inflammation & Allergy Drug Targets, 2012)
Cardiac or ventricular remodeling is characterized by molecular, cellular, and interstitial alterations that lead to changes in heart size, mass, geometry and function in response to a given insult. Currently, tobacco smoke ...
Influence of different doses of retinoic acid on cardiac remodeling
(Elsevier B.V., 2011-07-01)
Objective: The role of retinoic acid in promoting postnatal heart alterations is still unclear. The aim of this study was to evaluate whether the cardiac alterations caused by all-trans- retinoic acid (ATRA) in normal adult ...
Effects of late exercise on cardiac remodeling and myocardial calcium handling proteins in rats with moderate and large size myocardial infarction
(2016-10-15)
Background Physical exercise attenuates myocardial infarction (MI)-induced cardiac remodeling. However, it is unsettled whether late exercise modulates post-infarction cardiac remodeling differentially according to infarct ...
Heart remodeling produced by aortic stenosis promotes cardiomyocyte apoptosis mediated by collagen V imbalance
(2018-12-01)
Cardiac remodeling (CR) is a structural change of the heart due to chronic hemodynamic overload related to changes in both myocyte and extracellular matrix (ECM). We investigated that the imbalance of collagen V promotes ...
Physical training attenuates cardiac remodeling in rats with supra-aortic stenosis
(2014-01-01)
The aim of this study was to test the hypothesis that physical training (PT) attenuates cardiac remodeling and the severity of heart failure in rats with aortic stenosis. Wistar male rats were divided in sham (S, n=10), ...
Spondias mombin supplementation attenuated cardiac remodelling process induced by tobacco smoke
(2018-08-01)
The objective of this study was to investigate the influence of Spondias mombin (SM) supplementation on the cardiac remodelling process induced by exposure to tobacco smoke (ETS) in rats. Male Wistar rats were divided into ...
Pentoxifylline Attenuates Cardiac Remodeling Induced by Tobacco Smoke Exposure
(Arquivos Brasileiros Cardiologia, 2016-05-01)
Background: Tobacco smoke exposure is an important risk factor for cardiac remodeling. Under this condition, inflammation, oxidative stress, energy metabolism abnormalities, apoptosis, and hypertrophy are present. ...
Effects of obesity on the cardiac proteome
(2021-03-31)
Obesity has reached epidemic proportions in both developed and developing countries. It is currently recognized as a major health concern due to excessive adipose tissue which is associated with a wide range of other medical ...