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Association of type 2 diabetes mellitus and periodontal disease susceptibility with genome-wide association–identified risk variants in a Southeastern Brazilian population
(2021-01-01)
Objective: Genome-wide association studies (GWAS) and literature have identified polymorphisms in the KCNJ11, HNF1A, IRS1, TCF7L2, CDKAL1, CDKN2B, RPSAP52, GPR45 HHEX, IL18, and RUNX2 genes associated with type 2 diabetes ...
Erradicación de helicobacter pylori : una propuesta desde la farmacogenética y la epigenética en una población de Bogotá
(Pontificia Universidad Javeriana, 2020)
Identification of Altered Genes in Gallbladder Cancer as Potential Driver Mutations for Diagnostic and Prognostic Purposes: A Computational Approach
(SAGE, 2020)
Prognostic markers for cancer can assist in the evaluation of survival probability of patients and help clinicians to assess the available treatment modalities. Gallbladder cancer (GBC) is a rare tumor that causes 165 087 ...
Investigação genética e epigenética em pacientes com Síndrome de Beckwith-Wiedemann
(2018)
Os erros no padrão de imprinting são caracterizados como alterações epigenéticas por não afetarem a sequência nucleotídica do DNA mas modificarem a expressão gênica. Diversos aspectos do desenvolvimento embrionário, incluindo ...
Caracterização do gene RB1 e da região cromossômica 13q14 em portadores de deleções em RB1, e estudo de associação de polimorfismos do gene CDKN1B em portadores de retinoblastoma
(2018)
O retinoblastoma se inicia, na grande maioria dos casos, a partir de dois eventos mutacionais no gene RB1 nos retinoblastos. O rastreamento desse gene em portadores da doença e em seus familiares torna-se importante para ...
Meta-análise integrativa da expressão gênica global no músculo esquelético de peixes
(Universidade Estadual Paulista (Unesp), 2022-02-23)
O crescimento muscular dos peixes, o qual desperta grande interesse do setor produtivo, é regulado por múltiplos genes que fazem deste, um complexo processo ainda pouco compreendido. Nesse contexto, a reanálise do perfil ...
Oncogenic Actions of the Nuclear Receptor Corepressor (NCOR1) in a Mouse Model of Thyroid Cancer
(PUBLIC LIBRARY SCIENCE, 2013-06-26)
Studies have suggested that the nuclear receptor corepressor 1 (NCOR1) could play an important role in human cancers. However, the detailed molecular mechanisms by which it functions in vivo to affect cancer progression ...
Genome scan for postmortem carcass traits in nellore cattle
(2016-10-01)
Carcass traits measured after slaughter are economically relevant traits in beef cattle. In general, the slaughter house payment system is based on HCW. Ribeye area (REA) is associated with the amount of the meat in the ...
Genome scan for postmortem carcass traits in Nellore cattle
(Amer Soc Animal Science, 2016-10-01)
Carcass traits measured after slaughter are economically relevant traits in beef cattle. In general, the slaughter house payment system is based on HCW. Ribeye area (REA) is associated with the amount of the meat in the ...