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Mostrando ítems 61-70 de 142
Estrutura cristalográfica da Purina nucleosídeo foslorilase do Mycobacterium tuberculosis
(Universidade Estadual Paulista (Unesp), 2005-08-18)
A Purina Nucleosídeo Fosforilase (PNP) catalisa a fosforólise de nucleosídeos de purina para suas respectivas bases e açucares (ribose ou desoxirribose) 1-fosfato. A PNP desempenha uma função central no metabolismo das ...
SYNTHESIS OF HUMAN ANGIOTENSINOGEN (1-17) CONTAINING ONE OF THE PUTATIVE GLYCOSYLATION BINDING-SITES AND ITS HYDROLYSIS BY HUMAN RENIN AND PORCINE PEPSIN
(Munksgaard Int Publ Ltd, 1991-10-01)
The N-terminal heptadecapeptide of human angiotensinogen (Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Asn-Glu-Ser-Thr-NH2), with the C-terminal carboxyl group amidated, was synthesized in order to study the role ...
Analysis of catalytic properties of tripeptidyl peptidase I (TTP-I), a serine carboxyl lysosomal protease, and its detection in tissue extracts using selective FRET peptide substrate
(Elsevier Science Inc, 2016)
Tripeptidyl peptidase I (TPP-I), also named ceroid lipofuscinosis 2 protease (CLN2p), is a serine carboxyl lysosomal protease involved in neurodegenerative diseases, and has both tripeptidyl amino- and endopeptidase ...
Characterization of a novel thermostable enzyme from thermus sp. 2.9 with phospholipase and acyltransferase activities
(Karger, 2019-01)
Phospholipases are classified in different enzyme families according to the ester bond they cleave within phospholipids. The use of phospholipases in industrial processes has prompted the search for new enzymes with ...
Estrutura cristalográfica da Purina nucleosídeo foslorilase do Mycobacterium tuberculosis
(Universidade Estadual Paulista (Unesp), 2005-08-18)
A Purina Nucleosídeo Fosforilase (PNP) catalisa a fosforólise de nucleosídeos de purina para suas respectivas bases e açucares (ribose ou desoxirribose) 1-fosfato. A PNP desempenha uma função central no metabolismo das ...
Characterization of a kinin inactivating serine endopeptidase H2 (kininase) from human urine using fluorogenic substrates
(Elsevier B.V., 1999-12-01)
We have previously described a kinin-inactivating endopeptidase (H2), which was purified 19-fold from human urine by DEAE-cellulose chromatography and gel filtration. the enzyme was inhibited 100% by PMSF, TPCK and pOHMB. ...
Defining the substrate specificity of mouse cathepsin P
(Elsevier B.V., 2005-03-01)
Cathepsin P is a recently discovered placental cysteine protease that is structurally related to the more ubiquitously expressed, broad-specificity enzyme, cathepsin L. We studied the substrate specificity requirements of ...
S3 to S3 ' subsite specificity of recombinant human cathepsin K and development of selective internally quenched fluorescent substrates
(Portland Press, 2003-08-01)
We have systematically examined the S3 to S3' subsite substrate specificity requirements of cathepsin K using internally quenched fluorescent peptides derived from the lead sequence Abz-KLRFSKQ-EDDnp [where Abz is ...
Snake venom metalloproteinases: Their role in the pathogenesis of local tissue damage
(2000-09-10)
The biochemical characteristics of hemorrhagic metalloproteinases isolated from snake venoms are reviewed, together with their role in the pathogenesis of the local tissue damage characteristic of crotaline and viperine ...
ACE-inhibitory peptides from bovine caseins released with peptidases from Maclura pomifera latex
(Elsevier Science, 2017-03)
In work reported here, a proteolytic extract prepared from Maclura pomifera latex was employed to hydrolyze bovine caseins. Densitograms of Tricine–sodium-dodecyl-sulfate–polyacrylamide-gel electrophoresis (SDS-PAGE) ...