Now showing items 1-10 of 130
A quantitative chemiluminescent method for studying replicative and stress-induced premature senescence in cell cultures
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008)
beta-Galactosidase (beta-Gal) activity is a widely accepted biomarker to detect senescence both in situ and in vitro. A cytochemical assay based on production of a blue-dyed precipitate that results from the cleavage of ...
Homeostasis of DNA integrity
Homeostasis comprises the tendency of an organism or cell to regulate their chemical processes that take place internally so as to maintain health, vital functions and stability, owing to the coordinated response of its ...
Senescence-associated β-galactosidase activity in the in vitro ovarian stromal fibroblastsActividad β-galactosidasa asociada con la senescencia en fibroblastos del estroma ovárico in vitroAtividade β-galactosidase associada com a senescência em fibroblastos do estroma ovariano in vitro
(Universidad del Rosario, 2011)
Modelagem lógica de senescência celular humana
(Universidade Federal de Santa MariaBRFísicaUFSMPrograma de Pós-Graduação em Física, 2012-12-12)
After the progressive telomere shortening in successive cell divisions, normal somatic cells undergo a growth arrest called cellular senescence that occurs due to incomplete DNA replication. Senescence can also be activated ...
Increased production of functional small extracellular vesicles in senescent endothelial cells
Small extracellular vesicles (EVs) are novel players in vascular biology. However, a thorough understanding of their production and function remains elusive. Endothelial senescence is a key feature of vascular ageing and ...
Benzyladenine sprays and senescent flowers removal on postproduction performance of Potted zinnia 'Profusion cherry'
'Profusion Cherry' is a dwarf zinnia with prospect for pot use in Brazil. The success of flowering potted plants depends on its performance during transport and on the period of time that it performs well indoors. Benzyladenine ...
HPV-18 E2 protein downregulates antisense noncoding mitochondrial RNA-2, delaying replicative senescence of human keratinocytes
(Impact Journals LLC, 2019)
© Villota et al. Human and mouse cells display a differential expression pattern of a family of mitochondrial noncoding RNAs (ncmtRNAs), according to proliferative status. Normal proliferating and cancer cells express a ...
RAC3 more than a nuclear receptor coactivator: A key inhibitor of senescence that is down-regulated in aging
(Nature Publishing Group, 2015-10)
Receptor-associated coactivator 3 (RAC3) is a nuclear receptor coactivator usually overexpressed in tumors that exerts oncogenicfunctions in the cytoplasm and the nucleus. Although as part of its oncogenic actions it was ...
Descrição Booleana para eventos celulares: construção de redes, topologia e análise dinâmica
(Universidade Federal de Santa MariaBRFísicaUFSMPrograma de Pós-Graduação em Física, 2012-01-13)
This work presents a methodology to describe the dynamics and topology of biological regulatory networks through the application of graph theory. We model these networks using Boolean rules and simulations performed with ...