Search

Now showing items 1-5 of 5

Ranolazine Exerts Potent Effects on Atrial Electrical Properties and Abbreviates Atrial Fibrillation Duration in the Intact Porcine Heart

KUMAR, Kapil; NEARING, Bruce D.; CARVAS, Marcelo; NASCIMENTO, Bruno C. G.; ACAR, Mariana; BELARDINELLI, Luiz; VERRIER, Richard L. (WILEY-BLACKWELL PUBLISHING, INC, 2009)

Introduction: In vitro studies and ambulatory ECG recordings from the MERLIN TIMI-36 clinical trial suggest that the novel antianginal agent ranolazine may have the potential to suppress atrial arrhythmias. However, there ...

Intrapericardial Ranolazine Prolongs Atrial Refractory Period and Markedly Reduces Atrial Fibrillation Inducibility in the Intact Porcine Heart

CARVAS, Marcelo; NASCIMENTO, Bruno C. G.; ACAR, Mariana; NEARING, Bruce D.; BELARDINELLI, Luiz; VERRIER, Richard L. (LIPPINCOTT WILLIAMS & WILKINS, 2010)

Introduction: Extensive experimental studies and clinical evidence (Metabolic Efficiency with Ranzolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndrome Thrombolysis in Myocardial Infarction-36 [MERLIN ...

Ranolazine for stable angina pectoris

Unknown author (Cochrane Collaboration, 2017)

BACKGROUND: Stable angina pectoris is a chronic medical condition with significant impact on mortality and quality of life; it can be macrovascular or microvascular in origin. Ranolazine is a second-line anti-anginal drug ...

Energy Metabolism in Cardiac Remodeling and Heart Failure

Gaiolla, Paula Schmidt Azevedo; Minicucci, Marcos Ferreira; Santos, Priscila P.; Paiva, Sergio Alberto Rupp de; Zornoff, Leonardo Antonio Mamede (2014)

Energy Metabolism in Cardiac Remodeling and Heart Failure

Universidade Estadual Paulista (UNESP); Faculdade de Medicina (2013-05-01)

Fatty acids are the main substrates used by mitochondria to provide myocardial energy under normal conditions. During heart remodeling, however, the fuel preference switches to glucose. In the earlier stages of cardiac ...