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High paracellular nutrient absorption in intact bats is associated with high paracellular permeability in perfused intestinal segments
(Company Of Biologists Ltd, 2014-09-01)
Water-soluble nutrients are absorbed by the small intestine via transcellular and paracellular mechanisms. Based on a few previous studies, the capacity for paracellular nutrient absorption seems greater in flying mammals ...
Intestinal Water Absorption Varies with Expected Dietary Water Load among Bats but Does Not Drive Paracellular Nutrient Absorption
(Univ Chicago Press, 2015-11-01)
Rapid absorption and elimination of dietary water should he particularly important to flying species and were predicted to vary with the water content of the natural diet. Additionally, high water absorption capacity was ...
Dietary and pharmacological compounds altering intestinal calcium absorption in humans and animals
(Cambridge University Press, 2015-12)
The intestine is the only gate for the entry of Ca to the body in humans and mammals. The entrance of Ca occurs via paracellular and intracellular pathways. All steps of the latter pathway are regulated by calcitriol and ...
Consensus hologram QSAR modeling for the prediction of human intestinal absorption
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
Consistent in silico models for ADME properties are useful tools in early drug discovery. Here, we report the hologram QSAR modeling of human intestinal absorption using a dataset of 638 compounds with experimental data ...
Intestinal perfusion indicates high reliance on paracellular nutrient absorption in an insectivorous bat Tadarida brasiliensis
(Elsevier, 2013-03)
Flying vertebrates have been hypothesized to have a high capacity for paracellular absorption of nutrients. This could be due to high permeability of the intestines to nutrient-sized molecules. We performed intestinal ...
Mecanismos de ação e controle da digestão de proteínas e peptídios em humanos
(1999-12-01)
This review aims to report the major control mechanisms of protein and peptides digestion of special interest in human patients. Regarding protein assimilation its digestive process begins at the stomach with some not so ...
Molecular aspects of intestinal calcium absorption
(W J G Press, 2015-06)
Intestinal Ca2+ absorption is a crucial physiological process for maintaining bone mineralization and Ca2+ homeostasis. It occurs through the transcellular and paracellular pathways. The first route comprises 3 steps: the ...
Ursodeoxycholic and deoxycholic acids: A good and a bad bile acid for intestinal calcium absorption
(Elsevier Science Inc, 2013-12)
The aim of this study was to investigate the effect of ursodeoxycholic acid (UDCA) on intestinal Ca2+ absorption and to find out whether the inhibition of this process caused by NaDOC could be prevented by UDCA. Chicks ...
Regulation of intestinal calcium absorption by luminal calcium content. Role of intestinal alkaline phosphatase
(Wiley VCH Verlag, 2014-04)
Scope: Intestinal alkaline phosphatase is a brush border enzyme that is stimulated by calcium. Inhibition of intestinal alkaline phosphatase increases intestinal calcium absorption. We hypothesized that intestinal alkaline ...
Regulation of intestinal calcium absorption by luminal calcium content. Role of intestinal alkaline phosphatase
(Wiley VCH Verlag, 2014-03)
Scope: Intestinal alkaline phosphatase is a brush border enzyme that is stimulated by calcium. Inhibition of intestinal alkaline phosphatase increases intestinal calcium absorption. We hypothesized that intestinal alkaline ...