Now showing items 1-10 of 166
Cardiac remodeling induced by 13-cis retinoic acid treatment in acne patients
Background: Currently, 13-cis-retinoic acid (13-cis-RA) is the most effective therapy for acne. Isotretinoin, a first-generation synthetic 13-cis-RA compound, is associated with numerous adverse effects. To investigate the ...
Cardiac remodeling induced by smoking: Concepts, relevance, and potential mechanisms
Cardiac or ventricular remodeling is characterized by molecular, cellular, and interstitial alterations that lead to changes in heart size, mass, geometry and function in response to a given insult. Currently, tobacco smoke ...
Remodelação cardíaca induzida pelo tabagismo (tabaquismo)
Previous studies accomplished by our group suggest that tobacco smoke exposure results in cardiac remodeling, with progressive ventricular dysfunction. However, the mechanisms involved in this process are not known. ...
Waist circumference, but not body mass index, is a predictor of ventricular remodeling after anterior myocardial infarction
Objective: The impact of obesity on ventricular remodeling after myocardial infarction (MI) is still poorly understood. Therefore, the aim of this study was to evaluate the role of waist circumference (WC) and body mass ...
Impact of the length of vitamin D deficiency on cardiac remodeling.
This study was aimed to evaluate the influence of vitamin D (VD) deficiency on cardiac metabolism, morphology, and function. Thus, we investigated the relationship of these changes with the length of the nutrient restriction. ...
Food restriction-induced myocardial dysfunction demonstrated by the combination of in vivo and in vitro studies
The aim of this study was to test the hypothesis that protein-calorie undernutrition decreases myocardial contractility jeopardizing ventricular function, and that ventricular dysfunction can be detected noninvasively. ...