Now showing items 1-10 of 269
The Netrin-4/Neogenin-1 axis promotes neuroblastoma cell survival and migration
(Impact Journals LLC, 2017)
Neogenin-1 (NEO1) is a transmembrane receptor involved in axonal guidance, angiogenesis, neuronal cell migration and cell death, during both embryonic development and adult homeostasis. It has been described as a dependence ...
High CD8(+) and absence of Foxp3(+) T lymphocytes infiltration in gallbladder tumors correlate with prolonged patients survival
(BIOMED Central Ltd., 2018)
Background: Gallbladder cancer (GBC), although infrequent in industrialized countries, has high incidence rates in certain world regions, being a leading cause of death among elderly Chilean women. Surgery is the only ...
Rapamycin requires AMPK activity and p27 expression for promoting autophagy-dependent Tsc2-null cell survival
Tuberous sclerosis complex (TSC) disease results from inactivation of the TSC1 or TSC2 gene, and is characterized by benign tumors in several organs. Because TSC tumorigenesis correlates with hyperactivation of mTORC1, ...
Regulation of cell survival by resveratrol involves inhibition of NFκB-regulated gene expression in prostate cancer cells
BACKGROUND. Polyphenols have been proposed as antitumoral agents. We have shown that resveratrol (RES) induced cell cycle arrest and promoted apoptosis in prostate cancer cells by inhibition of the PI3K pathway. The RES ...
Sonic hedgehog in cancer stem cells: A novel link with autophagy
The Sonic Hegdehog/GLI (SHH/GLI) pathway has been extensively studied for its role in developmental and cancer biology. During early embryonic development the SHH pathway is involved mainly in pattern formation, while in ...
High CD8+ and absence of Foxp3+ T lymphocytes infiltration in gallbladder tumors correlate with prolonged patients survival
(BioMed Central Ltd., 2018)
© 2018 The Author(s). Background: Gallbladder cancer (GBC), although infrequent in industrialized countries, has high incidence rates in certain world regions, being a leading cause of death among elderly Chilean women. ...
Productive infection of Piscirickettsia salmonis in macrophages and monocyte-like cells from rainbow trout, a possible survival strategy
Piscirickettsia salmonis is the etiologic agent of the salmonid rickettsial septicemia (SRS), an endemic disease which causes significant losses in salmon production. This intracellular bacterium is normally cultured in ...
ICDS 2011 meeting 'Signaling in cell death survival, proliferation and degeneration'
(NATURE PUBLISHING GROUP, 2012-01)
Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival
(Nature Publishing Group, 2017)
© 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.The IRE1-XBP1 signalling pathway is part of a cellular programme that protects against endoplasmic reticulum (ER) stress, but also controls ...