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OXIDATIVE STRESS IN THE CAROTID BODY: IMPLICATIONS FOR THE CARDIOVENTILATORY ALTERATIONS INDUCED BY OBSTRUCTIVE SLEEP APNEA
(INTECH, 2012)
The obstructive sleep apnea (OSA) syndrome is recognized as an independent risk factor for systemic hypertension. The OSA syndrome is characterized by cyclic episodes of oxygen desaturation due to the partial or complete ...
CAROTID BODY TRANSMITTERS ACTIONS ON RABBIT PETROSAL GANGLION IN VITRO
(SPRINGER, 2006)
The petrosal ganglion (PG) that innervate the carotid body (CB) are activated by transmitters released from the CB receptor (type I, glomus) cells, resulting in the carotid nerve (CN) chemosensory activity. Although the ...
ROLE OF ENDOTHELIN-1 ON THE ENHANCED CAROTID BODY ACTIVITY INDUCED BY CHRONIC INTERMITTENT HYPOXIA
(SPRINGER, 2006)
The systemic ventilatory and cardiovascular adjustments to hypoxia depend on the activation of peripheral chemoreceptors, mainly the carotid bodies (CBs). Intermittent hypoxia produces CB chemosensory excitation, which may ...
CAROTID CHEMOSENSORY NEURONS IN THE PETROSAL GANGLIA ARE EXCITED BY ACH AND ATP
(KLUWER ACADEMIC PUBLISHERS, 2003)
Several molecules have been proposed as excitatory transmitters between carotid body (CB) glomus (type I) cells and petrosal ganglion (PG) neurons (Eyzaguirre and Zapata, 1984; Gonzalez et al. 1994). Recently, experiments ...
NEUROGLOBIN, A NEW OXYGEN BINDING PROTEIN IS PRESENT IN THE CAROTID BODY AND INCREASES AFTER CHRONIC INTERMITTENT HYPOXIA
(SPRINGER, 2006)
Neuroglobin (Ngb), a 151-amino-acid protein with a predicted molecular mass of 17 kD was recently identified as a member of the vertebrate globin family (Burmester and Hankeln, 2004; Mammen et al., 2002). Ngb, is predominantly ...
CHRONIC INTERMITTENT HYPOXIA ENHANCES CAROTID BODY CHEMOSENSORY RESPONSES TO ACUTE HYPOXIA
(SPRINGER, 2006)
Chronic intermittent hypoxia (CIH), characterized by short episodes of hypoxia followed by normoxia, is a common feature of obstructive sleep apnea (OSA). It has been proposed that CIH enhances the hypoxic ventilatory ...