Aripiprazol é um antipsicótico atípico (AAt) frequentemente indicado para o tratamento agudo da mania, assim como para quadros mistos de transtorno bipolar (TB) tipo I e para o tratamento de manutenção do TB tipo I. A ...

OBJECTIVE: The assessment of the depressive component during mania has become critical for the accurate diagnosis of mixed states, which were defined very narrowly in the past classification systems before Diagnostic and ...

Although the bipolar disorder (BD) occurs almost with the same frequency in both genders, the phenomenology and the outcome of the illness differ between them. Nevertheless, there is evidence that women with BD show, more ...

Several studies have suggested an important role for brain-derived neurotrophic factor (BDNF) in the pathophysiology and therapeutics of bipolar disorder (BPD). The mechanisms underlying the therapeutic effects of lithium ...