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Comparative mechanical study of isolated papillary muscle from Wistar-Kyoto and Wistar rats
(1994-01-01)
Isolated papillary muscles have often been used in myocardial mechanical function studies. The objective of the present study was to compare the mechanical function of papillary muscle isolated from left ventricle between ...
Morphometric analysis of the phrenic nerve in male and female Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR)
(Associação Brasileira de Divulgação Científica, 2011)
Ventilatory differences between rat strains and genders have been described but the morphology of the phrenic nerve has not been investigated in spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) rats. A ...
DNA damage in wistar kyoto rats exercised during pregnancy
(2017-01-01)
Purpose: To evaluate DNA damage levels in pregnant rats undergoing a treadmill exercise program. Methods: Wistar Kyoto rats were allocated into two groups (n= 5 animals/group): non-exercise and exercise. The pregnant rats ...
Cardiac baroreflex is already blunted in eight weeks old spontaneously hypertensive rats
(2010-03-11)
Background. The literature did not evidence yet with which age spontaneously hypertensive rats (SHR) start to present baroreflex reduction. We endeavored to evaluate the baroreflex function in eight-week-old SHR. Methods. ...
Alpha(2)-adrenergic receptor distribution and density within the nucleus tractus solitarii of normotensive and hypertensive rats during development
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
The nucleus tractus solitarii (NTS), located in the brainstem, is one of the main nuclei responsible for integrating different signals in order to originate a specific and orchestrated autonomic response. Antihypertensive ...
Transcriptome analysis of nicotine-exposed cells from the brainstem of neonate spontaneously hypertensive and Wistar Kyoto rats
(NATURE PUBLISHING GROUP, 2010)
In this study, the effects of nicotine on global gene expression of cultured cells from the brainstem of spontaneously hypertensive rat (SHR) and normotensive Wistar Kyoto (WKY) rats were evaluated using whole-genome ...
Participação do Estado Contrátil e do Relaxamento Miocárdico na Disfunção Ventricular durante a Transição Hipertrofia-Falência Cardíaca
(1997-12-01)
Purpose - To investigate the participation of contractile state and relaxation in cardiac muscle dysfunction during the transition from stable hypertrophy to cardiac decompensation in aging spontaneously hypertensive rats ...
Intra-strain variations of baroreflex sensitivity in young Wistar-Kyoto rats
(CANADIAN SOC CLINICAL INVESTIGATION, 2009)
Purpose: To compare baroreflex sensitivity among conscious rats of the same strain. Methods: Male WKY rats (eight weeks old) were studied. Cannulas were inserted into the abdominal aortic artery through the right femoral ...