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Spironolactone is secure and reduces left ventricular hypertrophy in hemodialysis patients
(2015)
There is recent evidence that aldosterone play a role in the pathogenesis of cardiovascular disease in dialysis patients, which leads to the opportunity to block its actions for the benefit of these patients. In nondialytic ...
Tratamiento del hirsutismo con espironolactona y con espironolactona más dexametasona
(Sociedad Médica de Santiago, 2000)
Mechanisms Involved in the Beneficial Effects of Spironolactone after Myocardial Infarction
(2013-09-30)
Introduction:Our objective was to analyze the effect of spironolactone on cardiac remodeling after experimental myocardial infarction (MI), assessed by matricellular proteins levels, cardiac collagen amount and distribution, ...
Thermal decomposition of some diuretic agents
(1996-05-01)
Thermogravimetry-derivative thermogravimetry and differential scanning calorimetry were used to study the thermal behaviour of furosemide, hydrochlorothiazide, spironolactone, and amiloride hydrochloride. The results ...
The effects of 2 mg chlormadinone acetate/30 mcg ethinylestradiol, alone or combined with spironolactone, on cardiovascular risk markers in women with polycystic ovary syndrome
(ELSEVIER SCIENCE INCNEW YORK, 2012-09)
Background: Polycystic ovary syndrome (PCOS) is an endocrine disorder associated with metabolic dysfunction and changes in cardiovascular risk markers, and using oral contraceptives (OCs) may exert a further negative effect ...
Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1
(WILEY-BLACKWELLHOBOKEN, 2012)
Persistent beta-adrenergic receptor stimulation with isoproterenol is associated with cardiac hypertrophy as well as cardiac synthesis of angiotensin II. Serum- and glucocorticoid-regulated kinase type 1 (SGK-1) is a key ...