Now showing items 1-10 of 1202
Dissolution Enhancement and Characterization of Nimodipine Solid Dispersions with Poloxamer 407 or PEG 6000
(TAYLOR & FRANCIS INCPHILADELPHIA, 2012)
The solid dispersion approach is an alternative to increase drug solubility. Many carriers have been studied, but there is few information about poloxamer 407 (P407). Consequently, the objective of this study was to evaluate ...
Unexpected Performance of Physical Mixtures over Solid Dispersions on the Dissolution Behavior of Benznidazole from Tablets
This work investigated the feasibility of developing benznidazole (BZL) tablets, allowing fast, reproducible, and complete drug dissolution, by compressing BZL-Polyethylene Glycol (PEG) 6000 physical mixtures (PMs) and ...
Development and physicochemical characterization of solid dispersions containing praziquantel for the treatment of schistosomiasis
Praziquantel (PZQ) is an anthelminthic agent active against parasitic flatworms of the Schistosoma type and the most important drug for the treatment and morbidity control of schistosomiasis. In this study, a high-performance ...
Energy dispersive X-ray fluorescence spectrometric determination of lead after liquid-solid extraction with 1-(2-pyridylazo)-2-naphthol immobilized on silica.
(Soc Brasileira QuimicaSao PauloBrasil, 1996)
Development and Evaluation of Praziquantel Solid Dispersions in Sodium Starch Glycolate
(Pharmacotherapy GroupBenin CityNigéria, 2013)
Very fast dissolving acid carboxymethylcellulose-rifampicin matrix: development and solid-state characterization
(Elsevier Science, 2016-10)
One of the main obstacles to the successful treatment of tuberculosis is the poor and variable oral bioavailability of rifampicin (RIF), which is mainly due to its low hydrophilicity and dissolution rate. The aim of this ...
Development and evaluation of praziquantel solid dispersions in sodium starch glycolate
Purpose: To develop and characterize solid dispersions of praziquantel (PZQ) with sodium starch glycolate (SSG) for enhanced drug solubility. Methods: PZQ solid dispersion (SD) was prepared using co-precipitation method ...
The Preparation of Ternary Solid Dispersions of an Herbal Drug via Spray Drying of Liquid Feed
(TAYLOR & FRANCIS INC, 2010)
The present study aimed the preparation and characterization of ternary solid dispersions by direct spray drying of a liquid suspension containing curcumin, a solubility enhancer and a drying aid. The experiments followed ...