Now showing items 1-10 of 106
Aerobic exercise training in heart failure: impact on sympathetic hyperactivity and cardiac and skeletal muscle function
(Associação Brasileira de Divulgação Científica, 2011)
Heart failure is a common endpoint for many forms of cardiovascular disease and a significant cause of morbidity and mortality. Chronic neurohumoral excitation (i.e., sympathetic hyperactivity) has been considered to be a ...
Heart failure-induced skeletal myopathy in spontaneously hypertensive rats
Background: Although skeletal muscle atrophy and changes in myosin heavy chain (MyHC) isoforms have often been observed during heart failure, their pathophysiological mechanisms are not completely defined. In this study ...
Insights from genotype-phenotype correlations by novel SPEG mutations causing centronuclear myopathy
Centronuclear myopathies (CNM) are a clinically and genetically heterogeneous group of congenital myopathies, defined histologically by increased number of fibres with centrally located nuclei, and type I fibre predominance ...
Skeletal Muscle for Endomyocardial Biopsy: Comparable Stress Response in Doxorubicin Cardio-myopathy
(Journal Toxicology and Pathology, 2013)
Electrophysiological evaluation in myotonic dystrophy - Correlation with CTG length expansion
(Assoc Arquivos De Neuro- PsiquiatriaSao Paulo SpBrasil, 2001)
Modulation of MAPK and NF-κB Signaling Pathways by Antioxidant Therapy in Skeletal Muscle of Heart Failure Rats
Background/Aims: Although increased oxidative stress plays a role in heart failure (HF)-induced skeletal myopathy, signaling pathways involved in muscle changes and the role of antioxidant agents have been poorly addressed. ...
Physical exercise among patients with systemic autoimmune myopathies
(BioMed Central, 2018)
Abstract Systemic autoimmune myopathies (SAMs) are a heterogeneous group of rare systemic autoimmune diseases that primarily affect skeletal muscles. Patients with SAMs show progressive skeletal muscle ...
Heart failure alters matrix metalloproteinase gene expression and activity in rat skeletal muscle
(Blackwell Publishing, 2006-12-01)
Heart failure is associated with a skeletal muscle myopathy with cellular and extracellular alterations. The hypothesis of this investigation is that extracellular changes may be associated with enhanced mRNA expression ...
Dynamin-2 in nervous system disorders
Dynamin-2 is a pleiotropic GTPase whose best-known function is related to membrane scission during vesicle budding from the plasma or Golgi membranes. In the nervous system, dynamin-2 participates in synaptic vesicle ...