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Basal lamina disorganisation of the acini and ducts of labial salivary glands from patients with Sjögren's syndrome: Association with mononuclear cell infiltration
(2006)
Objective: To study the expression of laminin and type IV collagen as biomarkers of the organisation of the basal lamina of acini and ducts in labial salivary glands from patients with Sjögren's syndrome, and to relate ...
Oral dryness in Sjögren's syndrome patients. Not just a question of water
(2013)
Sjögren's syndrome (SS) is a chronic autoimmune disease of undefined etiology. Patients with this syndrome suffer from severe alterations in both the quality and quantity of saliva and tears, due to impaired function of ...
Loss of the disease-associated glycosyltransferase Galnt3 alters Muc10 glycosylation and the composition of the oral microbiome
(American Society for Biochemistry and Molecular Biology, 2020)
The importance of the microbiome in health and its disruption in disease is continuing to be elucidated. However, the multitude of host and environmental factors that influence the microbiome are still largely unknown. ...
Sjögren's syndrome and the epithelial target: A comprehensive review
(2013)
The most difficult component in our understanding of human autoimmunity remains a rigorous dissection of etiological events. Indeed, the vast literature on autoimmune diseases focuses on the inflammatory response, with the ...
T cell exosome–derived miR-142-3p impairs glandular cell function in Sjögren’s syndrome
(The American Society for Clinical Investigation, 2020)
Sjogren's syndrome (SS) is a systemic autoimmune disease that mainly affects exocrine salivary and lacrimal glands. Local inflammation in the glands is thought to trigger glandular dysfunction and symptoms of dryness. ...
Reduced sulfation of MUC5B is linked to xerostomia in patients with Sjögren syndrome
(2008)
Objectives: MUC5B contains sulfated and sialylated
oligosaccharides that sequester water required for
moisturising the oral mucosa. Xerostomia, in patients with
Sjo¨gren syndrome, is generally associated with ...
Ecografía de la glándula salival mayor en pacientes con síndrome seco: descripción de una cohorte colombiana, reporte preliminar
(Asociación Colombiana de ReumatologíaColombia, 2020-08-20)
Introducción
El síndrome de Sjögren (SS) es una enfermedad autoinmune que afecta a las glándulas exocrinas condicionando síndrome seco. Los criterios diagnósticos se basan en pruebas serológicas, oftalmológicas, ...
Adenosis poliquística esclerosante de glándula parótida. Reporte de caso
(Sociedad Latinoamericana de PatologíaMéxico, 2016-01)
La adenosis poliquística esclerosante es una entidad rara, descrita
recientemente, que afecta a las glándulas salivares mayores con predominio en la glándula parótida. La etiología aún no es clara e histológicamente se ...
Endoplasmic reticulum stress in autoimmune diseases: Can altered protein quality control and/or unfolded protein response contribute to autoimmunity? A critical review on Sjögren's syndrome
(Elsevier B.V., 2018)
© 2018 Elsevier B.V. For many years, researchers in the field of autoimmunity have focused on the role of the immune components in the etiopathogenesis of autoimmune diseases. However, some studies have demonstrated the ...