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Clinical and haemodynamic evaluation of chronic thromboembolic pulmonary hypertension patients scheduled for pulmonary thromboendarterectomy: Is schistosomiasis hypertension an important confounding factor?
(Faculdade de Medicina / USP, 2010)
INTRODUCTION: Chronic thromboembolic pulmonary hypertension is a disease affecting approximately 4,000 people per year in the United States. The incidence rate in Brazil, however, is unknown. The estimated survival for ...
Revisiting the role of TRP, orai, and ASIC channels in the pulmonary arterial response to hypoxia
(Frontiers Media S.A., 2018)
© 2018 Reyes, Castillo-Galán, Hernandez, Herrera, Ebensperger and Llanos. The pulmonary arteries are exquisitely responsive to oxygen changes. They rapidly and proportionally contract as arterial PO2 decrease, and they ...
2-Aminoethyldiphenylborinate modiﬁes the pulmonary circulation in pulmonary hypertensive newborn lambs partially gestated at high altitude
(Amer Physiological Soc., 2016-10)
Calcium signaling through store-operated channels (SOC) is involved in hypoxic pulmonary hypertension. We determined whether a treatment with 2-aminoethyldiphenylborinate (2-APB), a compound with SOC blocker activity, ...
Fractal dimension in quantifying experimental-pulmonary-hypertension-induced cardiac dysfunction in rats
Background: Right-sided heart failure has high morbidity and mortality, and may be caused by pulmonary arterial hypertension. Fractal dimension is a differentiated and innovative method used in histological evaluations ...
Sildenafil selectively inhibits acute pulmonary embolism-induced pulmonary hypertension
(Academic Press Ltd Elsevier Science LtdLondonInglaterra, 2005)
Updated Clinical Classification of Pulmonary Hypertension
(ELSEVIER SCIENCE INC, 2009)
The aim of a clinical classification of pulmonary hypertension (PH) is to group together different manifestations of disease sharing similarities in pathophysiologic mechanisms, clinical presentation, and therapeutic ...
2-Aminoethyldiphenylborinate modifies the pulmonary circulation in pulmonary hypertensive newborn lambs partially gestated at high altitude
(American Physiological Society, 2016)
© 2016 the American Physiological Society. Calcium signaling through store-operated channels (SOC) is involved in hypoxic pulmonary hypertension. We determined whether a treatment with 2-aminoethyldiphenylborinate (2-APB), ...
Adrenomedullin induces pulmonary vasodilation but does not attenuate pulmonary hypertension in a sheep model of acute pulmonary embolism
(Elsevier B. V., 2015-10-15)
The pulmonary vasodilation induced by adrenomedullin may be beneficial in the acute pulmonary embolism (APE) setting. This study examined effects of adrenomedullin in sheep with microsphere-induced APE. Twenty four ...
Melatonin decreases pulmonary vascular remodeling and oxygen sensitivity in pulmonary hypertensive newborn lambs
(Frontiers media SA, 2018)
Background: Chronic hypoxia and oxidative stress during gestation lead to pulmonary hypertension of the neonate (PHN), a condition characterized by abnormal pulmonary arterial reactivity and remodeling. Melatonin has strong ...
Melatonina reduz alterações deletérias cardíacas e pulmonares em ratos portadores de hipertensão arterial pulmonar induzida por monocrotalina = Melatonin reduces cardiac and pulmonary deleterius alterations in disabled pulmonary arterial hypertension monocrotaline induced ratsMelatonin reduces cardiac and pulmonary deleterius alterations in disabled pulmonary arterial hypertension monocrotaline induced rats