Now showing items 1-10 of 967
Behavioral and molecular analysis of nicotine-conditioned place preference in zebrafish
(Public Library of Science, 2013-07)
Studies using mice and rats have demonstrated that nicotine induces a conditioned place preference (CPP), with more effective results obtained by using biased procedures. Zebrafish have also been used as a model system to ...
Influence of nicotine and cotinine impregnation on the first step of periodontal regeneration: clot stabilization
This study analyzes the clot stabilization on root surfaces of teeth impregnated with cotinine and nicotine and the influence of the scaling in the adhesion of blood components, observing the influence of new exposition ...
Mecamylamine-precipitated nicotine withdrawal syndrome and its prevention with baclofen: An autoradiographic study of α4β2 nicotinic acetylcholine receptors in mice
A previous study from our laboratory showed that baclofen (BAC, GABAB receptor agonist) was able to prevent the behavioral expression of nicotine (NIC) withdrawal syndrome. To further investigate the mechanisms underlying ...
Differential behavioral and neuroendocrine effects of repeated nicotine in adolescent and adult rats
(Elsevier B.V., 2005-03-01)
Despite the high prevalence of tobacco abuse among adolescents, the neurobiology of nicotine addiction has been studied mainly in adult animals. Repeated administration of this drug to adult rats induces behavioral ...
Attenuation by baclofen of nicotine rewarding properties and nicotine withdrawal manifestations
Rationale:Nicotine is a major active ingredient in tobacco and plays a major role in tobacco addiction. In rodents, repeated nicotine administration produces behavioral responses related to its addictive properties, such ...
Thermal behaviour of nicotinic acid, sodium nicotinate and its compounds with some bivalent transition metal ions
(Elsevier B.V., 2014-01-10)
Solid-state M(L)(2)center dot nH(2)O compounds, where M stands for bivalent transition metals (Mn, Fe, Co, Ni, Cu and Zn), L is nicotinate and n = 0-4.5, have been synthesized. Characterization and thermal behaviour of ...
Effects of simultaneous exposure to stress and nicotine on nicotine-induced locomotor activation in adolescent and adult rats
(Associação Brasileira de Divulgação Científica (ABRADIC), 2012-01-01)
Preclinical studies have shown that repeated stress experiences can result in an increase in the locomotor response to the subsequent administration of drugs of abuse, a phenomenon that has been termed behavioral ...
Molecular modeling of the α9α10 nicotinic acetylcholine receptor subtype
This study reports the comparative molecular modeling, docking and dynamic simulations of human α9α10 nicotinic acetylcholine receptors complexed with acetylcholine, nicotine and α-conotoxin RgIA, using as templates the ...
Effects of Oral Nicotine on Rat Liver Stereology
(Sociedad Chilena de Anatomía, 2008)