Now showing items 1-10 of 321
A nitric oxide synthase inhibitor decreases 6-hydroxydopamine effects on tyrosine hydroxylase and neuronal nitric oxide synthase in the rat nigrostriatal pathway
(ELSEVIER SCIENCE BV, 2008)
There is evidence that nitric oxide plays a role in the neurotransmitter balance within the basal ganglia and in the pathology of Parkinson`s disease. In the present work we investigated in striatal 6-hydroxydopamine ...
Tolerance to the cataleptic effect that follows repeated nitric oxide synthase inhibition may be related to functional enzymatic recovery
(SAGE PUBLICATIONS LTD, 2010)
Systemic or intra-striatal acute administration of nitric oxide synthase (NOS) inhibitors causes catalepsy in rodents. This effect disappears after sub-chronic treatment. The aim of the present study was to investigate if ...
Altered expression of neuronal nitric oxide synthase in weaver mutant mice
(ELSEVIER SCIENCE BV, 2010)
The weaver mouse represents the only genetic animal model of gradual nigrostriatal dopaminergic neurodegeneration which is proposed as a pathophysiological phenotype of Parkinson`s disease. The aim of the present study was ...
Expression of neuronal isoform of nitric oxide synthase in spinal neurons of neonatal rats after sciatic nerve transection
(Elsevier Sci Ireland LtdClareIrlanda, 2001)
Expression of neuronal nitric oxide synthase in the hippocampal formation in affective disorders
(Associação Brasileira de Divulgação Científica, 2008)
Hippocampal output is increased in affective disorders and is mediated by increased glutamatergic input via N-methyl-D-aspartate (NMDA) receptor and moderated by antidepressant treatment. Activation of NMDA receptors by ...
Acute inhibition of nitric oxide synthesis induces anxiolysis in the plus maze test
(Elsevier Science BvAmsterdamHolanda, 1997)
Astrocytic nitric oxide triggers tau hyperphosphorylation in hippocampal neurons
Production of nitric oxide (NO) by glial cells has been proposed to mediate cytotoxic effects on neighboring neurons. Although extensive genetic data implicate the beta amyloid peptide (Aβ) in the neurodegenerative cascade ...
NADPH diaphorase is developmentally regulated in rat olfactory epithelium
(Lippincott Williams and Wilkins, 2001)
In vertebrate olfactory receptor neurons, NO synthase (NOS) has been detected in embryonic and early postnatal stages. However, expression of the enzyme in the mature epithelium is still controversial. We analyzed the ...