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Differentiation of porcine induced pluripotent stem cells (Pipscs) into neural progenitor cells (npcs)
(2021-06-01)
iPSC-derived neurons are attractive in vitro models to study neurogenesis and early phenotypic changes in mental illness, mainly when most animal models used in pre-clinical research, such as rodents, are not able to meet ...
Equivalent Neurogenic Potential of Wild-Type and GFP-Labeled Fetal-Derived Neural Progenitor Cells Before and After Transplantation Into the Rodent Hippocampus
(LIPPINCOTT WILLIAMS & WILKINS, 2011)
Introduction. The hippocampal formation is a specific structure in the brain where neurogenesis occurs throughout adulthood and in which the neuronal cell loss causes various demential states. The main goal of this study ...
Retinoic Acid-Treated Pluripotent Stem Cells Undergoing Neurogenesis Present Increased Aneuploidy and Micronuclei Formation
(PUBLIC LIBRARY SCIENCE, 2011)
The existence of loss and gain of chromosomes, known as aneuploidy, has been previously described within the central nervous system. During development, at least one-third of neural progenitor cells (NPCs) are aneuploid. ...
Harmine Stimulates Proliferation Of Human Neural Progenitors
(PEERJ IncLondon, 2016)
TGF-β pro-oligodendrogenic effects on adult SVZ progenitor cultures and its interaction with the Notch signaling pathway
(Wiley-liss, Div John Wiley & Sons Inc, 2018-02)
Adult neural progenitor cells (NPCs) are capable of differentiating into neurons, astrocytes, and oligodendrocytes throughout life. Notch and transforming growth factor β1 (TGF‐β) signaling pathways play critical roles in ...
Administration of Neural Precursor Cells Ameliorates Renal Ischemia-Reperfusion Injury
(KARGER, 2009)
In this study we evaluated whether administration of stem cells of neural origin (neural precursor cells, NPCs) could be protective against renal ischemia-reperfusion injury (IRI). We hypothesized that stem cell outcomes ...
Induced pluripotent stem cell-derived neural precursors improve memory, synaptic and pathological abnormalities in a mouse model of Alzheimer’s disease
(MDPI, 2021)
Alzheimer's disease (AD) is the most common type of dementia in the elderly population. The disease is characterized by progressive memory loss, cerebral atrophy, extensive neuronal loss, synaptic alterations, brain ...
Higher Vulnerability and Stress Sensitivity of Neuronal Precursor Cells Carrying an Alpha-Synuclein Gene Triplication
(Public Library of Science, 2014-11)
Parkinson disease (PD) is a multi-factorial neurodegenerative disorder with loss of dopaminergic neurons in the substantia nigra and characteristic intracellular inclusions, called Lewy bodies. Genetic predisposition, such ...
Estudio de sistemas nanométricos basados en lecitina como vehículos de oligonucleótidos en el tratamiento del cáncer de mama
(Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica, 2015)
The timing of neuronal development in adult hippocampal neurogenesis.
(SAGE Publications, 2006-12)
The granule cell layer (GCL) of the adult dentate gyrus (DG) is a heterogeneous structure formed by neurons of different ages because a significant proportion of neurons continues to be generated throughout life. The ...