Search
Now showing items 1-10 of 121
Mitochondrial fission and autophagy in the normal and diseased heart
(2010)
Sustained hypertension promotes structural, functional and metabolic remodeling of cardiomyocyte mitochondria. As long-lived, postmitotic cells, cardiomyocytes turn over mitochondria continuously to compensate for changes ...
Mitochondria, myocardial remodeling, and cardiovascular disease
(2012)
The process of muscle remodeling lies at the core of most cardiovascular diseases. Cardiac adaptation to pressure or volume overload is associated with a complex molecular change in cardiomyocytes which leads to anatomic ...
The role of mitochondrial fusion and StAR phosphorylation in the regulation of StAR activity and steroidogenesis
(Elsevier Ireland, 2015-06)
The steroidogenic acute regulatory (StAR) protein regulates the rate-limiting step in steroidogenesis, i.e. the delivery of cholesterol from the outer (OMM) to the inner (IMM) mitochondrial membrane. StAR is a 37-kDa protein ...
Mitochondrial Fusion and ERK Activity Regulate Steroidogenic Acute Regulatory Protein Localization in Mitochondria
(Public Library of Science, 2014-06)
The rate-limiting step in the biosynthesis of steroid hormones, known as the transfer of cholesterol from the outer to the inner mitochondrial membrane, is facilitated by StAR, the Steroidogenic Acute Regulatory protein. ...
Metabolic syndrome and antipsychotics: The role of mitochondrial fission/fusion imbalance
(Frontiers Media SA, 2018)
Second-generation antipsychotics (SGAs) are known to increase cardiovascular risk through several physiological mechanisms, including insulin resistance, hepatic steatosis, hyperphagia, and accelerated weight gain. There ...
COPPER DEFICIENCY ALTERS CELL BIOENERGETICS AND INDUCES MITOCHONDRIAL FUSION THROUGH UP-REGULATION OF MFN2 AND OPA1 IN ERYTHROPOIETIC CELLS
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2013)
COPPER DEFICIENCY ALTERS CELL BIOENERGETICS AND INDUCES MITOCHONDRIAL FUSION THROUGH UP - REGULATION OF MFN2 AND OPA1 IN ERYTHROPOIETIC CELLS
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2013)
COPPER DEFICIENCY ALTERS CELL BIOENERGETICS AND INDUCES MITOCHONDRIAL FUSION THROUGH UP - REGULATION OF MFN2 AND OPA1 IN ERYTHROPOIETIC CELLS
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2013)
INSULIN STIMULATES MITOCHONDRIAL FUSION AND FUNCTION IN CARDIOMYOCYTES VIA THE AKT-MTOR-NF KAPPA B-OPA-1 SIGNALING PATHWAY
(AMERICAN DIABETES ASSOCIATION, 2014)