Now showing items 1-10 of 158
Effects of buthionine sulfoximine nifurtimox and benznidazole upon trypanothione and metallothionein proteins in Trypanosoma cruzi
(Society of Biology of Chile, 2004)
Proteins rich in sulfhydryl groups, such as metallothionein, are present in several strains of the parasite Trypanosoma cruzi, the etiological agent of Chagas' disease. Metallothionein-like protein concentrations ranged ...
Effects of buthionine sulfoximine nifurtimox and benznidazole upon trypanothione and metallothionein proteins in Trypanosoma cruzi.
(Sociedad de Biología de Chile, 2004)
Expression of metallothionein in pleomorphic adenoma
Purpose: Pleomorphic adenoma (PA) is a benign salivary gland tumor (SGT) containing different cell types, including myoepithelial cells. Metallothionein (MT) is a protein that has multiple functions in various neoplasm and ...
Expression of metallothionein in ameloblastoma. A regulatory molecule?
BACKGROUND: Ameloblastoma is a benign odontogenic tumor, exhibiting local invasiveness and high rate of recurrence. Metallothionein is a protein associated with tumorigenesis, serving as prognostic factor in different ...
Loss of the metal binding properties of metallothionein induced by hydrogen peroxide and free radicals
The relationship between the metal-binding properties of metallothionein (MT) and its ability to interact with peroxides and free radicals was explored in vitro. The binding of 109Cd to MT and the thiol density of the ...
A baseline study of the metallothioneins induction and its reversibility in Neohelice granulata from the Bahía Blanca Estuary (Argentina)
Contamination by heavy metals causes serious effects in marine systems. Nowadays, the combination of chemical and biological data is recommended in monitoring programs. Metallothioneins (MT) are early-warning signals of ...
The role of histidine in a copper-specific metallothionein
Metallothioneins achieve metal binding specificity by modulation of their amino acid sequences through evolution. Non-coordinating residues seem to play a key role in this function, and among them histidine may be of ...
Arsenic exposure, profiles of urinary arsenic species, and polymorphism effects of glutathione-s-transferase and metallothioneins
(Elsevier Ltd, 2018)
© 2018 Elsevier Ltd This study assessed the effects of polymorphic variants of gutathione-S-transferase and metallothioneins on profiles of urinary arsenic species. Drinking groundwater from Margarita and San Fernando, ...