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Naltrexone effects on insulin sensitivity and insulin secretion in hyperandrogenic women
(1998)
A total of 12 women (24.2 ± 1.6 years old, BMI 36.7 ± 1.5 Kg/m2) with hyperandrogenism (HA) and with normal glucose tolerance test were studied to evaluate the involvement of endogenous opioids in the pathophysiology of ...
Insulin Resistance and Alzheimer's Disease: Molecular Links & Clinical Implications
(BENTHAM SCIENCE PUBL LTD, 2008-10)
Hyperinsulinemia as well as type II diabetes mellitus are among the risk factors for Alzheimer´s disease (AD).
However, the molecular and cellular basis that link insulin resistance disorders and diabetes with AD are far ...
Insulin autoimmune syndrome. Report of two cases Síndrome de hipoglicemia autoinmune. Primeros casos en Chile
(Sociedad Medica de Santiago, 2015)
© 2015, Sociedad Medica de Santiago. All rights reserved. Insulin autoimmune syndrome (IAS) is characterized by spontaneous hypoglycemia with extremely high insulin levels and the presence of circulating autoantibodies ...
Insulin/NFκB protects against ischemia-induced necrotic cardiomyocyte death
(Academic Press Inc., 2015)
In the heart, insulin controls key functions such as metabolism, muscle contraction and cell death. However, all studies have been focused on insulin action during reperfusion. Here we explore the cardioprotective action ...
Análogos de insulina: en búsqueda del reemplazo fisiológico
(2006)
Insulin analogues, developed by molecular engineering, have
structural changes in the A and B insulin chains. These modifications change their action
profile, rendering insulin replacement closer to physiology. Rapid ...
Relationship between insulin sensitivity and IGF-I sensitivity in low birth weight prepubertal children
(2008)
Background: Insulin-like growth factor-I (IGF-I) and insulin are structurally related proteins with similar receptors and signal transduction systems. Aim: We postulate that some low birth weight (LBW) children may have ...
Calcium signaling in insulin action on striated muscle
(Churchill Livingstone, 2014)
© 2014 Elsevier Ltd. Striated muscles (skeletal and cardiac) are major physiological targets of insulin and this hormone triggers complex signaling pathways regulating cell growth and energy metabolism. Insulin increases ...
Insulin resistance and polycystic ovary syndrome through life
(2012)
The heterogeneity of Polycystic Ovary Syndrome (PCOS) emphasizes the need for a consensual review of the data concerning its diagnosis and treatment and for determination of the relationship between the development of PCOS ...
Postprandial whole-body glycolysis is similar in insulin-resistant and insulin-sensitive non-diabetic humans
(Springer, 2012)
Aims/hypothesis Insulin resistance is characterised by impaired
glucose utilisation when measured by a euglycaemic–
hyperinsulinaemic clamp. We hypothesised that, in
response to postprandial conditions, non-diabetic ...
Perceived difficulties among primary care physicians for the prescription of insulin for diabetic patients Dificultades en la prescripción racional de insulina: La percepción de los médicos tratantes de enfermos diabéticos de atención primaria de salud
(Sociedad Medica de Santiago, 2010)
Background: Type 2 Diabetes Mellitus is not always treated successfully, in part due to the difficulties perceived by the medical community about the use of insulin. Aim: To identify the constraints perceived by primary ...