Now showing items 1-10 of 356
Endotoxin-induced vascular endothelial cell migration is dependent on TLR4/NF-κB pathway, NAD(P)H oxidase activation, and transient receptor potential melastatin 7 calcium channel activity
(Elsevier Ltd, 2014)
Endothelial dysfunction is decisive and leads to the development of several inflammatory diseases. Endotoxemia-derived sepsis syndrome exhibits a broad inflammation-induced endothelial dysfunction. We reported previously ...
Endothelial dysfunction in cardiovascular and endocrine-metabolic diseases: an update
(Associação Brasileira de Divulgação Científica, 2011)
The endothelium plays a vital role in maintaining circulatory homeostasis by the release of relaxing and contracting factors. Any change in this balance may result in a process known as endothelial dysfunction that leads ...
Suppression of transient receptor potential melastatin 4 expression promotes conversion of endothelial cells into fibroblasts via transforming growth factor/activin receptor-like kinase 5 pathway
(Lippincott Williams and Wilkins, 2015)
© 2015 Wolters Kluwer Health | Lippincott Williams & Wilkins.Objective: To study whether transient receptor potential melastatin 4 (TRPM4) participates in endothelial fibrosis and to investigate the underlying mechanism. ...
Aldosterone induces endothelial dysfunction in resistance arteries from normotensive and hypertensive rats by increasing thromboxane A(2) and prostacyclin
Background and purpose: The present study was designed to assess whether cyclooxygenase-2 (COX-2) activation is involved in the effects of chronic aldosterone treatment on endothelial function of mesenteric resistance ...
Oxidative stress in hypertensive patients induces an increased contractility in vein grafts independent of endothelial function
(Hindawi Publishing Corporation, 2011-08)
Objective. To evaluate the impact of oxidative stress on vascular reactivity to vasoconstrictors and on nitric oxide (NO) bioavailability in saphenous vein (SV) graft with endothelial dysfunction from hypertensive patients ...
Diet and Endothelial Function
(Sociedad de Biología de Chile, 2004)