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Desaturation and heme elevation during COVID-19 infection: a potential prognostic factor of heme oxygenase-1
Increased heme levels, anemia, and desaturation occur during infection. We aimed to
compare the levels of heme, heme oxygenase-1 (HO-1), ferritin, and bilirubin in coronavirus
disease 2019 (COVID-19) patients at different ...
Adaptive Potential of the Heme Oxygenase/Carbon Monoxide Pathway During Hypoxia
(Frontiers Media, 2020)
Heme oxygenase (HO) enzymes catalyze heme into biliverdin, releasing carbon monoxide (CO) and iron into circulation. These byproducts of heme degradation can have potent cytoprotective effects in the face of stressors such ...
A heme-degradation pathway in a blood-sucking insect
(National Academy of Sciences, 2020)
Heme-oxygenases during erythropoiesis in K562 and human bone marrow cells
(Public Library of Science, 2018)
Carbon monoxide: from toxin to endogenous modulator of cardiovascular functions
(Associação Brasileira de Divulgação Científica, 1999-01-01)
Carbon monoxide (CO) is a pollutant commonly recognized for its toxicological attributes, including CNS and cardiovascular effects. But CO is also formed endogenously in mammalian tissues. Endogenously formed CO normally ...
Heme oxygenase-1 (HO-1), a protective gene that prevents chronic graft dysfunction
(Elsevier B.V., 2005-02-15)
Heme oxygenase-1 (HO-1) is a stress-responsive enzyme that acts during inflammatory reactions as the rate-limiting step in the catabolism of heme, yielding equimolar amounts of iron (Fe), biliverdin, and the gas carbon ...
Transepithelial heme-iron transport: effect of heme oxygenase overexpression
(SPRINGER HEIDELBERG, 2011)
Heme Oxygenase-1 as a Modulator of Intestinal Inflammation Development and Progression
(2018)
Heme Oxygenase 1 (HMOX1) is an enzyme that catalyzes the reaction that degrades the heme group contained in several important proteins, such as hemoglobin, myoglobin, and cytochrome p450. The enzymatic reaction catalyzed ...
The heme oxygenase-carbon monoxide system in the regulation of cardiorespiratory function at high altitude
(2012)
Pulmonary arterial hypertension is one of the most serious pathologies that can affect the 140 million people living at altitudes over 2500. m. The primary emphasis of this review is pulmonary artery hypertension in mammals ...