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Anti-androgenic activities of diuron and its metabolites in male Nile tilapia (Oreochromis niloticus)
(Elsevier B.V., 2015-07-01)
Diuron (3-(3,4-dichlorophenyl)-1,1-dimethylurea) is a widely used herbicide which has been frequently detected in surface waters throughout the world. In vivo bioassay guided fractionation studies indicated that diuron may ...
Estrogenic activities of diuron metabolites in female Nile tilapia (Oreochromis niloticus)
(2016-03-01)
Some endocrine disrupting chemicals (EDCs) can alter the estrogenic activities of the organism by directly interacting with estrogen receptors (ER) or indirectly through the hypothalamus-pituitary-gonadal axis. Recent ...
Diuron metabolites and urothelial cytotoxicity: In vivo, in vitro and molecular approaches
(Elsevier B.V., 2013-12-15)
Diuron is carcinogenic to the rat urinary bladder at high dietary levels. The proposed mode of action (MOA) for diuron is urothelial cytotoxicity and necrosis followed by regenerative urothelial hyperplasia. Diuron-induced ...
Comparação dos efeitos do diuron formulado e técnico no urotélio e nos parâmetros reprodutivos de ratos wistar machos
(Universidade Estadual Paulista (UNESP), 2018-02-22)
Ratos Wistar expostos por dois anos ao diuron (3-(3,4-diclorofenil)-1,1-dimetilureia) produto técnico (PT) à 2500ppm pela ração desenvolveram alta incidência de tumores uroteliais, sendo esse herbicida classificado pela ...
Estudo dose-resposta do herbicida diuron[3-(3,4-diclorofenil)-1,1-dimetiluréia] no epitélio da bexiga de ratos Wistar machos
(Universidade Estadual Paulista (UNESP), 2010-02-25)
Diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] is a herbicide that in a previous longterm study with Wistar rats fed at 2,500 ppm concentration showed high incidence of urothelial tumors in both genders. Accordingly, ...
Transcriptional Profile of Diuron-Induced Toxicity on the Urinary Bladder of Male Wistar Rats to Inform Mode of Action
(Oxford University Press, 2011-08-01)
Diuron (3-(3,4-dichlorophenyl)-1,1-dimethylurea) is a substituted urea herbicide that induces rat urinary bladder urothelial tumors at high dietary levels (2500 ppm). The specific mode of action and molecular alterations ...
Effects of alkylphenols on the biotransformation of diuron and enzymes involved in the synthesis and clearance of sex steroids in juvenile male tilapia (Oreochromus mossambica)
(2016-11-01)
Previous studies using in vivo bioassay guided fractionation indicated that the herbicide diuron (3-(3,4-dichlorophenyl)-1,1-dimethylurea) and alkylphenol (AP)-containing surfactants were detected in fractions of extracts ...
Diuron-Induced Rat Bladder Epithelial Cytotoxicity
(Oxford University Press, 2012-12-01)
Diuron, a substituted urea herbicide, is carcinogenic to the rat urinary bladder at high dietary levels (2500 ppm). To further elucidate the mode of action, this study aimed to determine the time course and sequence of ...
Dose-response of diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] in the urothelial mucosa of Wistar rats
(2013-08-20)
Diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] is a herbicide that induced urothelial tumors in the urinary bladder of Wistar rats fed 2500. ppm during a long-term study. The currently suggested non-genotoxic mode of ...
Controle químico de biótipos de buva (Conyza canadensis e Conyza bonariensis) resistentes ao glyphosate
(Univ Federal Ceara, Dept Geol, 2010-07-01)
Studies were conducted at Estacao Experimental de Citricultura de Bebedouro, SP to evaluate the response of glyphosate-resistant horseweed and hairy fleabane biotypes to herbicides glyphosate, bromacil + diuron, diuron e ...