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Differential steroidogenic response of human luteal cell subpopulations
(Oxford University, 1996)
The differentia] capacity for steroid synthesis of human
luteal cell subpopulations was investigated in a well defined
cell culture system. Corpora lutea were enzymatically
dissociated, and the two cell types were ...
Bovine derived in vitro cultures generate heterogeneous populations of antigen presenting cells
(Frontiers Media, 2019)
Antigen presenting cells (APC) of the mononuclear phagocytic system include dendritic cells (DCs) and macrophages (Macs) which are essential mediators of innate and adaptive immune responses. Many of the biological functions ...
Synthesis of extracellular matrix components by somatic testicular cells from immature and pubertal rats
(1989)
Total testicular cells derived from immature and pubertal rats were cultured under long‐term conditions. Somatic adherent cells proliferated in culture and produced collagen and proteoglycans. Collagen synthesis accounted ...
Generation and characterization of bovine testicular organoids derived from primary somatic cell populations
(MDPI, 2022)
Simple Summary Organoids are 3D-cell culture systems composed of tissue-specific cells that create structures similar to those of their tissue of origin. Organoids have generated great interest in recent years, since they ...
Expression of multidrug resistance proteins in prostate cancer is related with cell sensitivity to chemotherapeutic drugs
(2009)
BACKGROUND. Multidrug resistance (MDR) proteins have been associated with the lack of chemotherapy response. Expression of these proteins has been described in the prostate, but there is no information about their role in ...
Vulnerability to a metabolic challenge following perinatal asphyxia evaluated by organotypic cultures: neonatal nicotinamide treatment
(Springer, 2017)
The hypothesis of enhanced vulnerability following perinatal asphyxia was investigated with a protocol combining in vivo and in vitro experiments. Asphyxia-exposed (AS) (by 21 min water immersion of foetuses containing ...
A novel method for isolation and culture of primary swine gastric epithelial cells
(Reino Unido, 2021-01-06)
Background: Culturing primary epithelial cells has a major advantage over tumor-derived or immortalized cell lines as long as their functional phenotype and genetic makeup are mainly maintained. The swine model has shown ...
Comparative metabolic analysis of CHO cell clones obtained through cell engineering, for IgG productivity, growth and cell longevity
(Plos one, 2015)
Cell engineering has been used to improve animal cells' central carbon metabolism. Due to the central carbon metabolism's inefficiency and limiting input of carbons into the TCA cycle, key reactions belonging to these ...
Trypanosoma cruzi calreticulin: In vitro modulation of key immunogenic markers of both canine tumors and relevant immune competent cells
(Elsevier, 2020)
Recombinant calreticulin from Trypanosoma cruzi (rTcCalr), the parasite responsible for Chagas' disease, binds to Canine Transmissible Venereal Tumor (CTVT) cells from primary cultures and to a canine mammary carcinoma ...
Dexamethasone and Monophosphoryl Lipid A-Modulated Dendritic Cells Promote Antigen-Specific Tolerogenic Properties on Naive and Memory CD4(+) T cells
(Frontiers Media, 2016)
Tolerogenic dendritic cells (DCs) are a promising tool to control T cell-mediated autoimmunity. Here, we evaluate the ability of dexamethasone-modulated and monophosphoryl lipid A (MPLA)-activated DCs [MPLA-tolerogenic DCs ...