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Efeito do lisinopril sobre parametros cardiacos e mortalidade no infarto experimental em ratos
(1997-03-01)
Purpose: To analyse the effect of early (<24 h) administration of lisinopril on ventricular remodeling and mortality after myocardial infarction (MI) in rats. Methods: Wistar rats weighing 200-250 g were submitted to ...
Fractal dimension in quantifying experimental-pulmonary-hypertension-induced cardiac dysfunction in rats
(2016-07-01)
Background: Right-sided heart failure has high morbidity and mortality, and may be caused by pulmonary arterial hypertension. Fractal dimension is a differentiated and innovative method used in histological evaluations ...
Cooperative binding of ETS2 and NFAT links erk1/2 and calcineurin signaling in the pathogenesis of cardiac hypertrophy
(Lippincott Williams & Wilkins, 2021)
Background: Cardiac hypertrophy is an independent risk factor for heart failure, a leading cause of morbidity and mortality globally. The calcineurin/NFAT (nuclear factor of activated T cells) pathway and the MAPK ...
Insuficiência cardíaca com fração de ejeção normal
(Sociedade Brasileira de Cardiologia (SBC), 2010-05-01)
A insuficiência cardíaca com fração de ejeção normal (ICFEN) é uma síndrome complexa que vem sendo largamente estudada, desde a última década. É causada por disfunção ventricular diastólica evidenciada por métodos ...
The effect of non-antihypertensive doses of angiotensin converting enzyme inhibitor on myocardial necrosis and hypertrophy in young rats with renovascular hypertension
(1999-05-06)
In renovascular hypertensive rats, low doses of angiotensin converting enzyme (ACE) inhibitors have been found to prevent myocardial hypertrophy independent of blood pressure level. This finding would suggest humoral rather ...